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<p>Meglumine antimoniate (MA), the current treatment for Cutaneous leishmaniasis (CL) fails in many cases. We thus determined the rate and determinants of this treatment failure by a prospective study, in which 180 CL patients were selected using simple non-random sampling method. All lesions were completely cured in 127 patients (74.7%) but treatment failed in 43 patients (25.3%). Male sex and lesions on the face were the only factors associated with treatment failure.</p>

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Identifying determinants of treatment failure with intralesional meglumine antimoniate in patients with cutaneous leishmaniasis

  • 期刊论文

  • 发表日期：

    2026年3月10日

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  • Elaheh Andakhshideh,
  • Mohammad Javad Yazdanpanah,
  • Bita Kiafar,
  • Vahid Mashayekhi Goyonlo,
  • Mona Najaf Najafi,
  • Mobin Dorost

摘要

Meglumine antimoniate (MA), the current treatment for Cutaneous leishmaniasis (CL) fails in many cases. We thus determined the rate and determinants of this treatment failure by a prospective study, in which 180 CL patients were selected using simple non-random sampling method. All lesions were completely cured in 127 patients (74.7%) but treatment failed in 43 patients (25.3%). Male sex and lesions on the face were the only factors associated with treatment failure.