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Introduction <p>The increasing incidence of fractures and cases of delayed union or nonunion has encouraged the search for non-invasive therapies. Extracorporeal shockwave therapy (ESWT) has been proposed as a strategy to stimulate bone regeneration and improve fracture healing.</p> Materials and methods <p>A systematic review was conducted following PRISMA guidelines, with searches performed in PubMed, Scopus, Web of Science, and Embase (2005–2025). Clinical studies evaluating ESWT for fracture treatment with radiographic assessment of bone healing and the presence of a control group were included.</p> Results <p>A total of 834 studies were initially identified, of which 7 were included in the final analysis. Most studies demonstrated positive effects of ESWT, including improved bone healing, pain reduction, and functional recovery. However, there was considerable heterogeneity in treatment protocols and relatively small sample sizes.</p> Conclusion <p>ESWT shows potential as a non-invasive therapy to stimulate fracture healing, particularly in cases of delayed union or nonunion. However, further controlled clinical trials and standardized protocols are needed to confirm its clinical effectiveness.</p>

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Extracorporeal shockwave therapy in bone fractures: a systematic review

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月24日

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  • Thatiane Izabele Ribeiro Santos,
  • Lais Caroline Souza e Silva,
  • Mirian Bonifacio,
  • Cassia Maria Campos Melo,
  • Bruna Genari Sena,
  • Mariana Carvalho Simões,
  • Julia Risso Parisi,
  • Ana Caroline da Silva Fernandes,
  • Helena Mayumi Akashi,
  • Flavia de Oliveira,
  • Ana Claudia Muniz Renno

摘要

Introduction

The increasing incidence of fractures and cases of delayed union or nonunion has encouraged the search for non-invasive therapies. Extracorporeal shockwave therapy (ESWT) has been proposed as a strategy to stimulate bone regeneration and improve fracture healing.

Materials and methods

A systematic review was conducted following PRISMA guidelines, with searches performed in PubMed, Scopus, Web of Science, and Embase (2005–2025). Clinical studies evaluating ESWT for fracture treatment with radiographic assessment of bone healing and the presence of a control group were included.

Results

A total of 834 studies were initially identified, of which 7 were included in the final analysis. Most studies demonstrated positive effects of ESWT, including improved bone healing, pain reduction, and functional recovery. However, there was considerable heterogeneity in treatment protocols and relatively small sample sizes.

Conclusion

ESWT shows potential as a non-invasive therapy to stimulate fracture healing, particularly in cases of delayed union or nonunion. However, further controlled clinical trials and standardized protocols are needed to confirm its clinical effectiveness.