<p>Amyloidosis denotes a&#xa0;group of rare, but often fatal diseases which result from abnormal folding and deposition of insoluble proteins with subsequent organ damage especially of the heart and the kidneys. Histologic identification of amyloid by Congo red staining and by immunohistochemistry in the musculoskeletal system by orthopedic pathology especially in specimens from surgery for carpal tunnel syndrome, lumbar spinal stenosis and spontaneous tendon rupture, but also from other sites of the musculoskeletal system may facilitate early diagnosis and treatment of amyloidosis. Appropriate techniques for the detection of amyloid should be included in the routine diagnostic workup of all rheumatologic pathology specimens.</p>

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Amyloidosen in der orthopädisch/rheumatologischen Pathologie

  • Jonathan Falk,
  • Stephan Falk,
  • Veit Krenn

摘要

Amyloidosis denotes a group of rare, but often fatal diseases which result from abnormal folding and deposition of insoluble proteins with subsequent organ damage especially of the heart and the kidneys. Histologic identification of amyloid by Congo red staining and by immunohistochemistry in the musculoskeletal system by orthopedic pathology especially in specimens from surgery for carpal tunnel syndrome, lumbar spinal stenosis and spontaneous tendon rupture, but also from other sites of the musculoskeletal system may facilitate early diagnosis and treatment of amyloidosis. Appropriate techniques for the detection of amyloid should be included in the routine diagnostic workup of all rheumatologic pathology specimens.