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What is already known <p>• Sex-related differences in cardiovascular disease presentation, management, and outcomes have been increasingly recognized in recent years.</p> <p>• Women with acute cardiovascular conditions often receive less aggressive diagnostic and therapeutic interventions compared to men, particularly in the setting of acute coronary syndromes.</p> What this study adds <p>• This study provides a comprehensive evaluation of sex-related differences in a contemporary cohort of patients admitted to the Cardiac Intensive Care Unit (CICU), highlighting distinct admission patterns and management disparities.</p> <p>• Women with cardiovascular disease tend to be older at presentation, exhibit different risk factor profiles, and show distinct clinical manifestations compared to men.</p> <p>• It identifies higher mortality rates for women with STEMI and pulmonary embolism, emphasizing the need for improved recognition and tailored management of sex-specific differences in acute cardiovascular care.</p> Graphical Abstract <p></p>

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Sex-related presentation, outcome, and treatment in CICU: the SPOTlight STUDY

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月8日

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  • Alessia d’Aiello,
  • Mattia Brecciaroli,
  • Simone Filomia,
  • Daniela Pedicino,
  • Marco Giuseppe Del Buono,
  • Gianluigi Saponara,
  • Rocco Antonio Montone,
  • Gaetano Pinnacchio,
  • Lorenzo Genuardi,
  • Laura Antenucci,
  • Jacopo Lenkowicz,
  • Giovanna Liuzzo,
  • Carlo Trani,
  • Francesco Burzotta,
  • Tommaso Sanna

摘要

What is already known

• Sex-related differences in cardiovascular disease presentation, management, and outcomes have been increasingly recognized in recent years.

• Women with acute cardiovascular conditions often receive less aggressive diagnostic and therapeutic interventions compared to men, particularly in the setting of acute coronary syndromes.

What this study adds

• This study provides a comprehensive evaluation of sex-related differences in a contemporary cohort of patients admitted to the Cardiac Intensive Care Unit (CICU), highlighting distinct admission patterns and management disparities.

• Women with cardiovascular disease tend to be older at presentation, exhibit different risk factor profiles, and show distinct clinical manifestations compared to men.

• It identifies higher mortality rates for women with STEMI and pulmonary embolism, emphasizing the need for improved recognition and tailored management of sex-specific differences in acute cardiovascular care.

Graphical Abstract