Scholarlink

Purpose <p>Shunt thrombosis is an important complication after proximal splenorenal shunt (PSRS) in children with extrahepatic portal vein thrombosis (EHPVT). We evaluated whether preoperative vascular parameters are associated with postoperative PSRS patency.</p> Methods <p>Of 139 non-cirrhotic patients who underwent PSRS for EHPVT, 86 with adequate preoperative imaging and follow-up were included in this retrospective single-center study. The aortomesenteric angle, splenic and left renal vein diameter were measured on preoperative CT, and spontaneous splenorenal shunt presence was recorded. Shunt patency was assessed from postoperative imaging. Correlation, Firth penalized logistic regression, and ROC analyses were performed.</p> Results <p>Mean age was 114 ± 50 months; mean follow-up 81 ± 51 months. Patency was preserved in 69 patients (80.2%) and 17 (19.8%) developed thrombosis. No parameter was associated with patency: aortomesenteric angle (<i>r</i> = 0.035), splenic vein diameter (<i>r</i> = 0.039), left renal vein diameter (<i>r</i> = 0.111), or spontaneous splenorenal shunt (<i>r</i> = 0.005) (all <i>p</i> &gt; 0.05). Firth regression identified no independent predictors, and the aortomesenteric angle showed non-significant discrimination (AUC = 0.64, 95% CI 0.485–0.795, <i>p</i> = 0.076).</p> Conclusion <p>Preoperative vascular parameters were not associated with postoperative PSRS patency in pediatric EHPVT. Static anatomical measurements have limited predictive value for shunt outcomes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Preoperative vascular parameters and proximal splenorenal shunt patency in pediatric extrahepatic portal vein thrombosis

  • 期刊论文

  • 发表日期：

    2026年7月12日

查看全文
  • İsmail Akdulum,
  • Mehmet Narin,
  • Merve Yazol,
  • İhsan Yalçınkaya,
  • Ayşe Can,
  • Buket Dalgıç,
  • Aydın Dalgıç,
  • Sinan Sarı,
  • Öznur Leman Boyunağa

摘要

Purpose

Shunt thrombosis is an important complication after proximal splenorenal shunt (PSRS) in children with extrahepatic portal vein thrombosis (EHPVT). We evaluated whether preoperative vascular parameters are associated with postoperative PSRS patency.

Methods

Of 139 non-cirrhotic patients who underwent PSRS for EHPVT, 86 with adequate preoperative imaging and follow-up were included in this retrospective single-center study. The aortomesenteric angle, splenic and left renal vein diameter were measured on preoperative CT, and spontaneous splenorenal shunt presence was recorded. Shunt patency was assessed from postoperative imaging. Correlation, Firth penalized logistic regression, and ROC analyses were performed.

Results

Mean age was 114 ± 50 months; mean follow-up 81 ± 51 months. Patency was preserved in 69 patients (80.2%) and 17 (19.8%) developed thrombosis. No parameter was associated with patency: aortomesenteric angle (r = 0.035), splenic vein diameter (r = 0.039), left renal vein diameter (r = 0.111), or spontaneous splenorenal shunt (r = 0.005) (all p > 0.05). Firth regression identified no independent predictors, and the aortomesenteric angle showed non-significant discrimination (AUC = 0.64, 95% CI 0.485–0.795, p = 0.076).

Conclusion

Preoperative vascular parameters were not associated with postoperative PSRS patency in pediatric EHPVT. Static anatomical measurements have limited predictive value for shunt outcomes.