Scholarlink

Purpose <p>To analyze the clinical characteristics and identify independent predictors of intussusception secondary to pathological lead points (PLPs).</p> Methods <p>We conducted a retrospective study of children surgically treated for intussusception between 2010 and 2025. Patients were categorized into PLPs and non-PLPs groups. Demographic, clinical, laboratory, imaging, surgical, and pathological data were compared between the groups.</p> Results <p>Of 575 children included, 126 (21.9%) had PLPs and 449 (78.1%) were idiopathic. PLPs encompassed a range of etiologies, including Meckel’s diverticulum, intestinal duplications, polyps, tumors, and inflammatory conditions. Multivariable logistic regression identified seven independent predictors: older age (OR = 1.023, 95% CI: 1.014–1.032; <i>p</i> &lt; 0.001), the absence of hematochezia (OR = 0.472, 95% CI: 0.268–0.832; <i>p</i> = 0.009), the absence of vomiting (OR = 0.480, 95% CI: 0.242–0.954; <i>p</i> = 0.036), recurrence (OR = 2.313, 95% CI: 1.185–4.513; <i>p</i> = 0.014), small-intestinal intussusception (OR = 2.505, 95% CI: 1.370–4.581; <i>p</i> = 0.003), elevated thrombocytocrit (PCT) (OR = 23.850, 95% CI: 4.902-116.014; <i>p</i> &lt; 0.001), and the presence of ascites (OR = 2.002, 95% CI: 1.209–3.315; <i>p</i> = 0.007).</p> Conclusions <p>Older age, hematochezia, vomitus, recurrence intussusception, small-intestinal intussusception, thrombocytocrit and ascites are independent predictors of PLPs and may aid in risk stratification and guide the decision for surgical intervention.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Clinical characteristics and predictors for the presence of pediatric intussusception secondary to pathological lead points

  • 期刊论文

  • 发表日期：

    2026年6月20日

查看全文
  • Yuan-Yang Yu,
  • Yi-Xuan Wei,
  • Zhong-Zhe Ren,
  • Mu-Kun Guan,
  • Hui-Ya Huang,
  • Xiao-Zhong Huang

摘要

Purpose

To analyze the clinical characteristics and identify independent predictors of intussusception secondary to pathological lead points (PLPs).

Methods

We conducted a retrospective study of children surgically treated for intussusception between 2010 and 2025. Patients were categorized into PLPs and non-PLPs groups. Demographic, clinical, laboratory, imaging, surgical, and pathological data were compared between the groups.

Results

Of 575 children included, 126 (21.9%) had PLPs and 449 (78.1%) were idiopathic. PLPs encompassed a range of etiologies, including Meckel’s diverticulum, intestinal duplications, polyps, tumors, and inflammatory conditions. Multivariable logistic regression identified seven independent predictors: older age (OR = 1.023, 95% CI: 1.014–1.032; p < 0.001), the absence of hematochezia (OR = 0.472, 95% CI: 0.268–0.832; p = 0.009), the absence of vomiting (OR = 0.480, 95% CI: 0.242–0.954; p = 0.036), recurrence (OR = 2.313, 95% CI: 1.185–4.513; p = 0.014), small-intestinal intussusception (OR = 2.505, 95% CI: 1.370–4.581; p = 0.003), elevated thrombocytocrit (PCT) (OR = 23.850, 95% CI: 4.902-116.014; p < 0.001), and the presence of ascites (OR = 2.002, 95% CI: 1.209–3.315; p = 0.007).

Conclusions

Older age, hematochezia, vomitus, recurrence intussusception, small-intestinal intussusception, thrombocytocrit and ascites are independent predictors of PLPs and may aid in risk stratification and guide the decision for surgical intervention.