Scholarlink

Objective <p>To identify predictors of early recurrence after hydrostatic reduction of pediatric intussusception and develop a nomogram.</p> Methods <p>A total of 412 children with intussusception treated between January 2022 and January 2025 were enrolled. Based on recurrence within 48&#xa0;h after successful hydrostatic reduction, they were assigned to a recurrent group (n = 37) or a non-recurrent group (n = 375). Clinical and ultrasonographic variables were compared between the groups, and a nomogram was developed and validated from the identified predictors.</p> Results <p>Following hydrostatic reduction, some independent predictors of recurrent intussusception in children were identified: symptom-onset time, maximal “target-sign” diameter on ultrasound, concentric-ring anatomic location, bowel-wall thickness, presence of intraluminal lesions, and peritoneal effusion (P &lt; 0.05). A nomogram that integrates these ultrasound indices with clinical variables exhibited excellent calibration and discrimination. Decision-curve analysis further confirmed that the model delivered greater net clinical benefit than either “treat-all” or “treat-none” strategies across the entire range of threshold probabilities.</p> Conclusion <p>In this study, we developed a nomogram based on clinical risk factors to predict short-term recurrence of intussusception after ultrasound-guided hydrostatic reduction in children. Age, duration of abdominal pain, maximal diameter of the “target sign” on ultrasound, concentric-ring anatomic location, bowel-wall thickness, intraluminal lesions, and peritoneal effusion were identified as predictors and incorporated into the model. Internal validation demonstrated that this nomogram provides a clear and convenient tool for stratifying recurrence risk in children undergoing ultrasound-guided hydrostatic reduction.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Risk factors for early recurrence after hydrostatic reduction of intussusception in children and development of a nomogram prediction model

  • 期刊论文

  • 发表日期：

    2026年3月9日

查看全文
  • Xin Li,
  • Hongjia Qiang,
  • Zhaozheng Ding,
  • Xiangjie Li,
  • Yuan Cao,
  • Dongsheng Zhu

摘要

Objective

To identify predictors of early recurrence after hydrostatic reduction of pediatric intussusception and develop a nomogram.

Methods

A total of 412 children with intussusception treated between January 2022 and January 2025 were enrolled. Based on recurrence within 48 h after successful hydrostatic reduction, they were assigned to a recurrent group (n = 37) or a non-recurrent group (n = 375). Clinical and ultrasonographic variables were compared between the groups, and a nomogram was developed and validated from the identified predictors.

Results

Following hydrostatic reduction, some independent predictors of recurrent intussusception in children were identified: symptom-onset time, maximal “target-sign” diameter on ultrasound, concentric-ring anatomic location, bowel-wall thickness, presence of intraluminal lesions, and peritoneal effusion (P < 0.05). A nomogram that integrates these ultrasound indices with clinical variables exhibited excellent calibration and discrimination. Decision-curve analysis further confirmed that the model delivered greater net clinical benefit than either “treat-all” or “treat-none” strategies across the entire range of threshold probabilities.

Conclusion

In this study, we developed a nomogram based on clinical risk factors to predict short-term recurrence of intussusception after ultrasound-guided hydrostatic reduction in children. Age, duration of abdominal pain, maximal diameter of the “target sign” on ultrasound, concentric-ring anatomic location, bowel-wall thickness, intraluminal lesions, and peritoneal effusion were identified as predictors and incorporated into the model. Internal validation demonstrated that this nomogram provides a clear and convenient tool for stratifying recurrence risk in children undergoing ultrasound-guided hydrostatic reduction.