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Purpose <p>Pediatric negative pressure wound therapy (NPWT) is widely used, but etiology- and age-informed real-world benchmarks are limited. We compared treatment burden and closure trajectories across pediatric wound categories.</p> Methods <p>Retrospective single-center cohort of children (&lt; 18 years) treated with NPWT for open wounds (2020–2025). Wounds were categorized as surgical (G1), acute (G2), chronic (G3), and burns (G4). NPWT was performed in accordance with an age-adapted institutional protocol in continuous mode; dressing changes were usually performed every 72&#xa0;h.</p> Results <p>106 patients (median age 144 months, IQR 60–180) were included: G1 42, G2 22, G3 31, G4 11. Age distribution differed by group (<i>p</i> &lt; 0.001), and instillation use varied (<i>p</i> = 0.014). Duration was longest in G3 (median 13 [8,–24] days) and shortest in G4 (median 6 [5,–9] days), while G1 and G2 were similar. Median cycle counts were similar across groups. Re-debridement was least frequent in G1. Definitive outcomes differed by etiology: primary closure predominated in G1, secondary healing in G3, and spontaneous closure in G4; grafting occurred mainly in burns, and flap reconstruction was rare.</p> Conclusions <p>NPWT was feasible across heterogeneous pediatric wounds when used with a standardized, age-adapted approach. Etiology-specific differences in burden and outcomes inform expectations and support prospective multicenter evaluation.</p>

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Negative pressure wound therapy in children: outcomes across a heterogeneous wound cohort

  • 期刊论文

  • 发表日期：

    2026年3月6日

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  • Özkan Okur,
  • Zehra Tabak,
  • Mehmet Can,
  • Asya Eylem Boztas,
  • Ayse Demet Payza,
  • Incinur Genisol,
  • Arzu Şencan

摘要

Purpose

Pediatric negative pressure wound therapy (NPWT) is widely used, but etiology- and age-informed real-world benchmarks are limited. We compared treatment burden and closure trajectories across pediatric wound categories.

Methods

Retrospective single-center cohort of children (< 18 years) treated with NPWT for open wounds (2020–2025). Wounds were categorized as surgical (G1), acute (G2), chronic (G3), and burns (G4). NPWT was performed in accordance with an age-adapted institutional protocol in continuous mode; dressing changes were usually performed every 72 h.

Results

106 patients (median age 144 months, IQR 60–180) were included: G1 42, G2 22, G3 31, G4 11. Age distribution differed by group (p < 0.001), and instillation use varied (p = 0.014). Duration was longest in G3 (median 13 [8,–24] days) and shortest in G4 (median 6 [5,–9] days), while G1 and G2 were similar. Median cycle counts were similar across groups. Re-debridement was least frequent in G1. Definitive outcomes differed by etiology: primary closure predominated in G1, secondary healing in G3, and spontaneous closure in G4; grafting occurred mainly in burns, and flap reconstruction was rare.

Conclusions

NPWT was feasible across heterogeneous pediatric wounds when used with a standardized, age-adapted approach. Etiology-specific differences in burden and outcomes inform expectations and support prospective multicenter evaluation.