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Objective <p>The aim of this study was to evaluate the differences in physical examination and radiologic findings of patients with proximal hypospadias in terms of Disorders of Sex Development (DSD) groups.</p> Materials and Methods <p>The ages, physical examination and radiological findings and diagnoses of the cases aged 0–18 years who were admitted to our hospital due to proximal hypospadias between 2005 and 2022 and whose male gender was determined because of their evaluation for DSD were evaluated.</p> Results <p>The study population included 43 patients with a median age of 4 months (1&#xa0;day-14 years): 19 presented with penoscrotal, 13 with scrotal, and 11 with perineal hypospadias. All cases exhibited severe ventral chordee, with micropenis observed in most patients. 46,XY DSD represented most cases, followed by sex chromosome DSD, 46,XX DSD, and other karyotype anomalies. Most patients in the DSD group had undescended testes and/or micropenis. Penoscrotal hypospadias was seen only in the 46,XY DSD group and no uterine remnants were seen in this group.</p> Conclusion <p>Patients with proximal hypospadias accompanied by undescended testis and/or micropenis should be evaluated in detail before any surgical intervention. We believe that especially in cases with scrotal and perineal hypospadias should be investigated for possible uterine remnants.</p>

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In which cases of proximal hypospadias detailed investigations are necessary

  • 期刊论文

  • 发表日期：

    2026年3月4日

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  • Gökmen Aydınbaş,
  • Ayşe Karaman,
  • Semra Çetinkaya,
  • İbrahim Karaman

摘要

Objective

The aim of this study was to evaluate the differences in physical examination and radiologic findings of patients with proximal hypospadias in terms of Disorders of Sex Development (DSD) groups.

Materials and Methods

The ages, physical examination and radiological findings and diagnoses of the cases aged 0–18 years who were admitted to our hospital due to proximal hypospadias between 2005 and 2022 and whose male gender was determined because of their evaluation for DSD were evaluated.

Results

The study population included 43 patients with a median age of 4 months (1 day-14 years): 19 presented with penoscrotal, 13 with scrotal, and 11 with perineal hypospadias. All cases exhibited severe ventral chordee, with micropenis observed in most patients. 46,XY DSD represented most cases, followed by sex chromosome DSD, 46,XX DSD, and other karyotype anomalies. Most patients in the DSD group had undescended testes and/or micropenis. Penoscrotal hypospadias was seen only in the 46,XY DSD group and no uterine remnants were seen in this group.

Conclusion

Patients with proximal hypospadias accompanied by undescended testis and/or micropenis should be evaluated in detail before any surgical intervention. We believe that especially in cases with scrotal and perineal hypospadias should be investigated for possible uterine remnants.