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<p>Pediatric B-cell precursor lymphoblastic lymphoma (BCP-LBL) is a rare subtype of non-Hodgkin lymphoma with a predominantly extramedullary presentation. Cutaneous and subcutaneous involvement, particularly in the head region, is a recognized manifestation; however, presentation as a solitary scalp mass mimicking a benign surgical lesion remains diagnostically challenging. A 10-year-old female patient presented to the Neurosurgery Department for a growing mass in the right frontal region of the scalp for the past 4&#xa0;months. After excision, the mass was diagnosed as BCP-LBL and the patient was referred to oncologic treatment. This report aims to increase awareness among surgeons and physicians that persistent or progressive pediatric scalp lesions, even when clinically benign-appearing, may represent an underlying malignant hematologic disease requiring prompt histopathological verification and specialist referral.</p>

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An unusual cranial manifestation of B-cell precursor lymphoblastic lymphoma in 10-year-old girl

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年8月1日

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  • Dominika Bardońska,
  • Tymon Skadorwa,
  • Łukasz Hutnik

摘要

Pediatric B-cell precursor lymphoblastic lymphoma (BCP-LBL) is a rare subtype of non-Hodgkin lymphoma with a predominantly extramedullary presentation. Cutaneous and subcutaneous involvement, particularly in the head region, is a recognized manifestation; however, presentation as a solitary scalp mass mimicking a benign surgical lesion remains diagnostically challenging. A 10-year-old female patient presented to the Neurosurgery Department for a growing mass in the right frontal region of the scalp for the past 4 months. After excision, the mass was diagnosed as BCP-LBL and the patient was referred to oncologic treatment. This report aims to increase awareness among surgeons and physicians that persistent or progressive pediatric scalp lesions, even when clinically benign-appearing, may represent an underlying malignant hematologic disease requiring prompt histopathological verification and specialist referral.