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Purpose <p>Congenital encephaloceles are rare neurosurgical conditions often associated with other intracranial anomalies. This study describes the clinicopathologic profile, management, and outcomes of patients with encephalocele in a Nigerian hospital.</p> Methods <p>A 7-year retrospective review was conducted of patients managed for encephalocele in our institution. Data were collected in a structured proforma and analysed.</p> Results <p>There were 7 females and 5 males, aged 1 to 60&#xa0;days at presentation (median = 3&#xa0;days); mean paternal and maternal ages were 33.42 ± 3.70 and 29.25 ± 3.91&#xa0;years, with no reported maternal preconceptional folic acid use. The second-born child was most frequently affected (41.7%), and prenatal diagnosis was made in 3 patients; lesions were predominantly occipital (10) with 2 sincipital, and one case was giant (8.3%). Mean occipito-frontal circumference (OFC) was 34.96 ± 5.54&#xa0;cm, decreasing with increasing lesion size (<i>p</i> = 0.672); 3 patients had concomitant hydrocephalus (commoner in sincipital lesions, 50% vs. 20%, <i>p</i> = 0.455), all had CSF diversion during repair. Mean age at surgery was 29.83 ± 22.62&#xa0;days, mean operative time 129.17 ± 27.46&#xa0;min, estimated blood loss 40.42 ± 16.71&#xa0;mL, and blood volume transfused 49.17 ± 16.63&#xa0;mL; repair was translesional in 11 and transcranial in 1 patient. Postoperative complications included surgical site infections, hydrocephalus, seizures (2 each), and 1 recurrence. At 30-day follow-up, there was no mortality and all parents were satisfied with cosmetic outcomes.</p> Conclusion <p>While this study demonstrated favorable short-term outcomes, it also highlights the need for public health initiatives promoting routine maternal preconceptional folic acid use.</p>

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Clinicopathological profile, management and outcome of patients with congenital encephalocele: a Nigerian tertiary centre experience

  • 期刊论文

  • 发表日期：

    2026年1月29日

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  • Olukorede Olabanji Adekunle,
  • Olugbenga Timothy Odebode,
  • Nurudeen Abiola Adeleke,
  • Olakunle Michael Adegboye,
  • Oghenevwoke Enaworu,
  • Hakeem Ayinde Yeqeen,
  • Akingbade Adebayo AkinDosumu,
  • Nnara Onyeka Stanley

摘要

Purpose

Congenital encephaloceles are rare neurosurgical conditions often associated with other intracranial anomalies. This study describes the clinicopathologic profile, management, and outcomes of patients with encephalocele in a Nigerian hospital.

Methods

A 7-year retrospective review was conducted of patients managed for encephalocele in our institution. Data were collected in a structured proforma and analysed.

Results

There were 7 females and 5 males, aged 1 to 60 days at presentation (median = 3 days); mean paternal and maternal ages were 33.42 ± 3.70 and 29.25 ± 3.91 years, with no reported maternal preconceptional folic acid use. The second-born child was most frequently affected (41.7%), and prenatal diagnosis was made in 3 patients; lesions were predominantly occipital (10) with 2 sincipital, and one case was giant (8.3%). Mean occipito-frontal circumference (OFC) was 34.96 ± 5.54 cm, decreasing with increasing lesion size (p = 0.672); 3 patients had concomitant hydrocephalus (commoner in sincipital lesions, 50% vs. 20%, p = 0.455), all had CSF diversion during repair. Mean age at surgery was 29.83 ± 22.62 days, mean operative time 129.17 ± 27.46 min, estimated blood loss 40.42 ± 16.71 mL, and blood volume transfused 49.17 ± 16.63 mL; repair was translesional in 11 and transcranial in 1 patient. Postoperative complications included surgical site infections, hydrocephalus, seizures (2 each), and 1 recurrence. At 30-day follow-up, there was no mortality and all parents were satisfied with cosmetic outcomes.

Conclusion

While this study demonstrated favorable short-term outcomes, it also highlights the need for public health initiatives promoting routine maternal preconceptional folic acid use.