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<p>Central skull base osteomyelitis with sellar epidural abscess and neurovascular narrowing are a unique combination of imaging findings resulting from complicated acute paranasal sinusitis. Nonspecific clinical presentation and insidious onset with atypical initial imaging findings often pose a diagnostic challenge. We present two cases of acute sinusitis, which progressed to central skull base osteomyelitis and additional intracranial complications. Maintaining a high index of suspicion and a multidisciplinary approach during preoperative workup are essential for timely management.</p>

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Pediatric sinusitis complicated by skull base osteomyelitis and neurovascular narrowing—two cases and literature review

  • 期刊论文

  • 发表日期：

    2026年1月20日

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  • Alka Gupta,
  • Austin Moats,
  • Saurabh Gupta,
  • Savvas Andronikou

摘要

Central skull base osteomyelitis with sellar epidural abscess and neurovascular narrowing are a unique combination of imaging findings resulting from complicated acute paranasal sinusitis. Nonspecific clinical presentation and insidious onset with atypical initial imaging findings often pose a diagnostic challenge. We present two cases of acute sinusitis, which progressed to central skull base osteomyelitis and additional intracranial complications. Maintaining a high index of suspicion and a multidisciplinary approach during preoperative workup are essential for timely management.