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Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report

  • Amanda V. Jenson,
  • Ali Yunus Rizvi,
  • Rebecca A. Reynolds,
  • Sara Hartnett-Wright,
  • Thomas J. Gellar,
  • Stacie Stapleton,
  • Ignacio Gonzalez-Gomez,
  • S. Hassan A. Akbari,
  • Matthew D. Smyth

摘要

Teratomas account for 18–20% of all intracranial germ cell tumors and mostly occur in the pineal region with only a few cases of pediatric sellar and suprasellar teratomas described in the literature. Here, we present a case of a child with an intracranial mature teratoma with pancreatic features causing vasospasm and subsequent stroke, found to be positive for CDKN2A—an independent variant associated with malignancy and small vessel disease leading to stroke.