Risk factors associated with intraventricular hemorrhage in very-low-birth-weight premature infants

期刊论文
发表日期：

2024年2月13日

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Alejandra Guadalupe Puerta-Martínez,
Esteban López-Garrido,
José Miguel Guerrero-Nava,
Rodrigo Vargas-Ruiz,
Hadassa Yuef Martínez-Padrón

摘要

Purpose

To analyze the association between risk factors and severe intraventricular hemorrhage (grade II–IV) in PNB under 1500 g.

Methods

Multicenter, retrospective, analytical, case–control study in PNB under 34 weeks and under 1500 g admitted to the NICU. Case: PNB with severe intraventricular hemorrhage (grade II–IV). Logistic regression analysis was used to adjust for IVH-associated variables and odds ratios (OR).

Results

A total of 90 PNB files were analyzed, 45 cases and 45 controls. The highest risk factors for severe IVH were lower gestational age (OR 1.3, p < 0.001), perinatal asphyxia (OR 12, p < 0.001), Apgar < 6 at minute 1 and 5 (OR 6.3, p < 0.001).

Conclusion

Lower gestational age, birth asphyxia, Apgar score lower of 6, and respiratory-type factors are associated with increased risk for severe IVH.