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<p>A novel telemonitoring system utilizing contactless sensor technologies combined with automated overnight respiratory stability time (RST) analysis has emerged as a sensitive and specific indicator of early deteriorating heart failure (HF). However, the association between RST and clinical parameters, including hemodynamics, remains unclear. Patients admitted to our institute due to worsening HF between February and December 2025 and underwent RST monitoring and simultaneous right heart catheterization were enrolled in this study. The relationship between RST and patient characteristics, hemodynamic parameters, and clinical outcomes was retrospectively investigated. A total of 30 patients (median age, 75 years; 70% male) were included. RST was negatively correlated with the number of HF hospitalizations, serum creatinine, plasma B-type natriuretic peptide, pulmonary artery pressure and dose of loop diuretics. During a median follow-up of 178 days, a lower RST (≤ 25&#xa0;s) group showed a numerically higher cumulative incidence of the composite outcomes of HF readmission and all-cause death compared with the higher RST group (50.6% versus 0%, <i>p</i> = 0.019). Lower RST may reflect heart failure severity, including pulmonary congestion. Further research is warranted to establish the clinical efficacy of RST-guided HF management.</p>

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Respiratory stability time and heart failure severity

  • 期刊论文

  • 发表日期：

    2026年5月11日

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  • Makiko Nakamura,
  • Teruhiko Imamura,
  • Yuki Hida,
  • Toshihide Izumida,
  • Masaki Nakagaito,
  • Shuhei Tanaka,
  • Koichiro Kinugawa

摘要

A novel telemonitoring system utilizing contactless sensor technologies combined with automated overnight respiratory stability time (RST) analysis has emerged as a sensitive and specific indicator of early deteriorating heart failure (HF). However, the association between RST and clinical parameters, including hemodynamics, remains unclear. Patients admitted to our institute due to worsening HF between February and December 2025 and underwent RST monitoring and simultaneous right heart catheterization were enrolled in this study. The relationship between RST and patient characteristics, hemodynamic parameters, and clinical outcomes was retrospectively investigated. A total of 30 patients (median age, 75 years; 70% male) were included. RST was negatively correlated with the number of HF hospitalizations, serum creatinine, plasma B-type natriuretic peptide, pulmonary artery pressure and dose of loop diuretics. During a median follow-up of 178 days, a lower RST (≤ 25 s) group showed a numerically higher cumulative incidence of the composite outcomes of HF readmission and all-cause death compared with the higher RST group (50.6% versus 0%, p = 0.019). Lower RST may reflect heart failure severity, including pulmonary congestion. Further research is warranted to establish the clinical efficacy of RST-guided HF management.