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<p>The vitreous body is the largest structure of the human eye and is subject to special requirements to ensure optimal light transmission. Its specific arrangement of collagen fibrils and water bound to hyaluronan minimizes light scattering while providing stability. In addition, the vitreous body harbors a&#xa0;tissue-specific immune cell population adapted to its particular needs, the hyalocytes. These cells perform key tasks in the regression of embryonic vessels, tissue homeostasis and immune surveillance, thereby significantly contributing to the integrity and function of the vitreous body. Both alterations in the composition or embryonic development of the vitreous body as well as dysfunction of its tissue-specific immune cells can form the basis of pathological processes.</p>

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Ein Blick auf den Glaskörper, nicht durch ihn hindurch: Anatomie, Embryologie und Zellen des Glaskörpers

  • 期刊论文

  • 发表日期：

    2026年1月29日

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  • Quang Vinh Ngo,
  • P. Wieghofer,
  • H. Agostini,
  • C. Lange,
  • S. Boneva

摘要

The vitreous body is the largest structure of the human eye and is subject to special requirements to ensure optimal light transmission. Its specific arrangement of collagen fibrils and water bound to hyaluronan minimizes light scattering while providing stability. In addition, the vitreous body harbors a tissue-specific immune cell population adapted to its particular needs, the hyalocytes. These cells perform key tasks in the regression of embryonic vessels, tissue homeostasis and immune surveillance, thereby significantly contributing to the integrity and function of the vitreous body. Both alterations in the composition or embryonic development of the vitreous body as well as dysfunction of its tissue-specific immune cells can form the basis of pathological processes.