Scholarlink

Purpose <p>This study evaluates the association between Nutcracker Syndrome (NCS) and adolescent varicocele, focusing on hemodynamic parameters, symptom patterns, and diagnostic thresholds to optimize clinical management.</p> Methods <p>In this prospective study, 56 adolescents (mean age 14.9 ± 2.1 years) with Grade II-III varicocele underwent standardized Doppler ultrasonography to assess pampiniform plexus diameters, SMA-Aorta angles, and renal vein dynamics. NCS was defined as a standing SMA-Aorta angle &lt; 30°. Groups were stratified by NCS status and pampiniform plexus diameter (≥ 2.8&#xa0;mm vs. &lt;2.8&#xa0;mm). Symptom profiles (pain, palpable mass) and hemodynamic differences were analyzed (Tables&#xa0;2 and 3).</p> Results <p>NCS prevalence was 71.4%. NCS(+) patients had lower BMI (<i>p</i> = 0.018), growth percentiles (<i>p</i> = 0.003), and narrower SMA-Aorta angles (standing: 16.9° vs. 26.6°, <i>p</i> &lt; 0.001). Pampiniform plexus diameters were larger in NCS(+) cases (resting: 3.0 vs. 2.2&#xa0;mm, <i>p</i> &lt; 0.001). When the groups were evaluated in terms of isolated pain, no difference was found between them (<i>p</i> = 1.000), while NCS(-) patients had higher pain-mass combination scores (<i>p</i> = 0.012). When cases with pampiniform plexus diameter ≥ 2.8&#xa0;mm were compared, significant associations were demonstrated: larger Valsalva diameters (4.50 vs. 3.01&#xa0;mm, <i>p</i> &lt; 0.001), narrower SMA-Aorta angles (standing: 17.3° vs. 21.4°, <i>p</i> = 0.008), and lower BMI percentile values (<i>p</i> = 0.008) were observed.</p> Conclusion <p>NCS is prevalent in adolescent varicocele and linked to distinct hemodynamic and anthropometric profiles. Key findings include: Symptom paradox: NCS(−) patients reported more pain-mass combinations (<i>p</i> = 0.012). Diagnostic thresholds: Pampiniform diameter ≥ 2.8&#xa0;mm and standing SMA-Aorta angle &lt; 25° are critical markers. Routine postural Doppler screening is recommended for adolescents with varicocele, especially those with low BMI.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Beyond venous dilatation: Nutcracker syndrome and Its Unique Hemodynamic Signature in Adolescent Varicocele

  • 期刊论文

  • 发表日期：

    2025年11月15日

查看全文
  • Yavuz Yilmaz,
  • Nadide Basak Gulleroglu,
  • Fatih Turgul,
  • Fatih Akbiyik

摘要

Purpose

This study evaluates the association between Nutcracker Syndrome (NCS) and adolescent varicocele, focusing on hemodynamic parameters, symptom patterns, and diagnostic thresholds to optimize clinical management.

Methods

In this prospective study, 56 adolescents (mean age 14.9 ± 2.1 years) with Grade II-III varicocele underwent standardized Doppler ultrasonography to assess pampiniform plexus diameters, SMA-Aorta angles, and renal vein dynamics. NCS was defined as a standing SMA-Aorta angle < 30°. Groups were stratified by NCS status and pampiniform plexus diameter (≥ 2.8 mm vs. <2.8 mm). Symptom profiles (pain, palpable mass) and hemodynamic differences were analyzed (Tables 2 and 3).

Results

NCS prevalence was 71.4%. NCS(+) patients had lower BMI (p = 0.018), growth percentiles (p = 0.003), and narrower SMA-Aorta angles (standing: 16.9° vs. 26.6°, p < 0.001). Pampiniform plexus diameters were larger in NCS(+) cases (resting: 3.0 vs. 2.2 mm, p < 0.001). When the groups were evaluated in terms of isolated pain, no difference was found between them (p = 1.000), while NCS(-) patients had higher pain-mass combination scores (p = 0.012). When cases with pampiniform plexus diameter ≥ 2.8 mm were compared, significant associations were demonstrated: larger Valsalva diameters (4.50 vs. 3.01 mm, p < 0.001), narrower SMA-Aorta angles (standing: 17.3° vs. 21.4°, p = 0.008), and lower BMI percentile values (p = 0.008) were observed.

Conclusion

NCS is prevalent in adolescent varicocele and linked to distinct hemodynamic and anthropometric profiles. Key findings include: Symptom paradox: NCS(−) patients reported more pain-mass combinations (p = 0.012). Diagnostic thresholds: Pampiniform diameter ≥ 2.8 mm and standing SMA-Aorta angle < 25° are critical markers. Routine postural Doppler screening is recommended for adolescents with varicocele, especially those with low BMI.