Scholarlink

<p><i>Pseudomonas aeruginosa</i>, a key member of the ESKAPE pathogen group, is a common cause of urinary tract infections (UTIs), particularly in patients with indwelling urinary catheters. Due to its large genome, <i>P. aeruginosa</i> has a high potential for genetic mutations, enabling the development of multidrug resistance. Additionally, it produces a variety of virulence factors, which contribute to persistent and often refractory infections. While UTIs caused by <i>Escherichia coli</i> have been extensively studied, those caused by <i>P. aeruginosa</i> remain less well understood. Understanding the mechanisms underlying the occurrence and progression of <i>P. aeruginosa</i>-associated UTIs, as well as the evolution of its antimicrobial resistance, is crucial for developing more effective treatment strategies. This paper provides an overview of the interaction between <i>P. aeruginosa</i> and UTIs, offering insights that could aid in more effective management and eradication of <i>P. aeruginosa</i> in the urinary tract.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Cross-talk between Pseudomonas aeruginosa and urinary tract infections

  • 期刊论文

  • 发表日期：

    2025年6月20日

查看全文
  • Xiao-Quan Yu,
  • Yu-Wen Gong,
  • Jun-Qiang Tian,
  • Cheng Peng,
  • Shao-Min Niu,
  • Han-Zhong Feng,
  • Chong-Ge You,
  • Zhi-Ping Wang

摘要

Pseudomonas aeruginosa, a key member of the ESKAPE pathogen group, is a common cause of urinary tract infections (UTIs), particularly in patients with indwelling urinary catheters. Due to its large genome, P. aeruginosa has a high potential for genetic mutations, enabling the development of multidrug resistance. Additionally, it produces a variety of virulence factors, which contribute to persistent and often refractory infections. While UTIs caused by Escherichia coli have been extensively studied, those caused by P. aeruginosa remain less well understood. Understanding the mechanisms underlying the occurrence and progression of P. aeruginosa-associated UTIs, as well as the evolution of its antimicrobial resistance, is crucial for developing more effective treatment strategies. This paper provides an overview of the interaction between P. aeruginosa and UTIs, offering insights that could aid in more effective management and eradication of P. aeruginosa in the urinary tract.