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Background <p>Multiple surgical approaches have been provided for treating Stress urinary incontinence (SUI) combined with anterior vaginal wall prolapse (cystocele). However the optimal treatment remains a topic of ongoing debate. This systematic review and single-arm analysis aimed to evaluate the efficacy and safety of midurethral sling (MUS) with concomitant anterior colporrhaphy (AC) for surgical treatment of stress urinary incontinence associated with grade 1–3 anterior vaginal wall prolapse.</p> Methods <p>We searched through multiple databases including, PubMed, Cochrane, Scopus, and Web of Science using a well-established search strategy to identify studies assessing the outcomes of MUS with concomitant AC in women with SUI and grade 1–3 cystocele. Data was extracted from the relevant studies in a predefined excel sheet. Data analysis was accomplished by using OpenMeta [analyst] software.</p> Results <p>We found 744 articles and included eight studies in the analysis. The pooled objective cure rate of SUI was 0.907 (95% CI 0.871 to 0.943), objective failure of SUI was 0.036 (95% CI 0.002 to 0.071), the subjective cure rate was 0.825 (95% CI 0.717 to 0.932), and the anatomical success rate for cystocele was 0.919 (95% CI 0.851 to 0.987). De novo urge urinary incontinence was reported in 12 of 81 patients, and four of 46 patients developed de novo OAB symptoms. Postoperative retention was noted in 5% of 405 patients. Long-term follow-up data from two studies indicated a durable effect.</p> Conclusion <p>MUS combined with AC is an effective option for treating SUI associated with grade 1–3 cystocele, with high rates of both objective and subjective cure.</p>

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Outcomes of concomitant midurethral sling and anterior colporrhaphy in managing stress urinary incontinence associated with cystocele: a systematic review and single-arm analysis

  • 期刊论文

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  • 发表日期：

    2025年7月30日

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  • Mohamed Tharwat,
  • Reham Ramadan,
  • Mohamed Abd-ElGawad,
  • Abdelwahab Hashem,
  • Diaa-Eldin Taha

摘要

Background

Multiple surgical approaches have been provided for treating Stress urinary incontinence (SUI) combined with anterior vaginal wall prolapse (cystocele). However the optimal treatment remains a topic of ongoing debate. This systematic review and single-arm analysis aimed to evaluate the efficacy and safety of midurethral sling (MUS) with concomitant anterior colporrhaphy (AC) for surgical treatment of stress urinary incontinence associated with grade 1–3 anterior vaginal wall prolapse.

Methods

We searched through multiple databases including, PubMed, Cochrane, Scopus, and Web of Science using a well-established search strategy to identify studies assessing the outcomes of MUS with concomitant AC in women with SUI and grade 1–3 cystocele. Data was extracted from the relevant studies in a predefined excel sheet. Data analysis was accomplished by using OpenMeta [analyst] software.

Results

We found 744 articles and included eight studies in the analysis. The pooled objective cure rate of SUI was 0.907 (95% CI 0.871 to 0.943), objective failure of SUI was 0.036 (95% CI 0.002 to 0.071), the subjective cure rate was 0.825 (95% CI 0.717 to 0.932), and the anatomical success rate for cystocele was 0.919 (95% CI 0.851 to 0.987). De novo urge urinary incontinence was reported in 12 of 81 patients, and four of 46 patients developed de novo OAB symptoms. Postoperative retention was noted in 5% of 405 patients. Long-term follow-up data from two studies indicated a durable effect.

Conclusion

MUS combined with AC is an effective option for treating SUI associated with grade 1–3 cystocele, with high rates of both objective and subjective cure.