Conservative treatment of Peyronie’s disease: a guide

期刊论文
发表日期：

2024年5月13日

查看全文

Marco Cosentino,
Michele Di Nauta,
Luca Boeri,
Giordana Ferraioli,
Gianpaolo Lucignani,
Anna Ricapito,
Franco Gadda,
Massimo Iafrate,
Mariangela Mancini,
Fabrizio Dal Moro,
Eduard Ruiz-Castañe,
Carlo Bettocchi,
Emanuele Montanari,
Nikolaos Sofikitis

摘要

Purpose

To review the literature on the topic, to suggest a common line of treatment applicable across a wide community of specialists, and to contribute in maintaining the high level of interest in this disease.

Methods

A comprehensive and exhaustive review of the literature was performed, identifying hundreds of articles on the topic.

Results

Peyronie’s disease is a condition that has been recognized, studied, and treated for centuries; despite this, if one excludes surgery in cases in which the deformity is stable, no clear treatment (or line of treatment) is available for complete relief of signs and symptoms. Treatment options were divided into local, oral, and injection therapy, and a wide variety of drugs, remedies, and options were identified.

Conclusions

Low-intensity extracorporeal shock wave therapy, vacuum therapy, penile traction therapy, phosphodiesterase type 5 inhibitors, hyaluronic acid, and collagenase of Clostridium histolyticum may be recommended only in specific contexts. Further studies on individual options or potential combinations are required.