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<p>In this study, a novel approach was employed to enhance the effectiveness of the acid etching process in improving the biocompatibility and bioactivity of nanostructured commercially pure titanium (CP-Ti). For the first time, ultraviolet (UV) irradiation under a pure nitrogen atmosphere was integrated into a modified SLA-based method, termed SL-UV-A (sandblasting–UV irradiation–acid etching), and applied to nanostructured Ti pre-processed by severe plastic deformation. The SL-UV-A treated nanostructured CP-Ti demonstrated superior apatite formation after immersion in simulated body fluid (SBF) compared to other groups. In addition, the biocompatibility of the surfaces was assessed using pre-osteoblast MC3T3-E1 cells. The SL-UV-A treated nanostructured CP-Ti showed enhanced cell adhesion and viability. Results from the MTT assay confirmed the absence of cytotoxicity and revealed a denser distribution of cells on the SL-UV-A modified nanostructure titanium. Overall, the findings suggest that the SL-UV-A process significantly improves the biological performance of nanostructured titanium, making it a promising strategy to enhance the osseointegration of dental implants.</p>

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Surface characteristics of nanostructured titanium surface modified via UV irradiation during SLA

  • 期刊论文

  • 发表日期：

    2025年7月18日

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  • S. Khorasani,
  • G. Faraji

摘要

In this study, a novel approach was employed to enhance the effectiveness of the acid etching process in improving the biocompatibility and bioactivity of nanostructured commercially pure titanium (CP-Ti). For the first time, ultraviolet (UV) irradiation under a pure nitrogen atmosphere was integrated into a modified SLA-based method, termed SL-UV-A (sandblasting–UV irradiation–acid etching), and applied to nanostructured Ti pre-processed by severe plastic deformation. The SL-UV-A treated nanostructured CP-Ti demonstrated superior apatite formation after immersion in simulated body fluid (SBF) compared to other groups. In addition, the biocompatibility of the surfaces was assessed using pre-osteoblast MC3T3-E1 cells. The SL-UV-A treated nanostructured CP-Ti showed enhanced cell adhesion and viability. Results from the MTT assay confirmed the absence of cytotoxicity and revealed a denser distribution of cells on the SL-UV-A modified nanostructure titanium. Overall, the findings suggest that the SL-UV-A process significantly improves the biological performance of nanostructured titanium, making it a promising strategy to enhance the osseointegration of dental implants.