<p>A unique hollow core PCF with a decagonal shape, produced by an optical waveform, is created and analytically evaluated. In this paper, on the basis of refractive indices (RI), we detected the most common cancer cells, especially cervical carcinoma, which emerged from HeLa. Additionally, the properties of the guiding of the designed waveguide have been examined. In terms of FEM, a computational tool Comsol Multiphysics 5.6 Software’s are utilized for analyse salient features of the proposed cancer cell sensor. Additionally, to construct the graph of every result, Paint and MATLAB 18a are also used. With regard to cancer cells and normal cells, this detector achieves a relative sensitivity of around 99.845% and 99.50% and CL is 6.24 × 10<sup>− 11</sup> dB/m and 2.66 × 10<sup>− 12</sup> dB/m at 3.2 THz. This biosensor offers an extremely reliable and precise method for fast detection of Cancer Cell. The innovative method enhances the capability to seance and identify certain diseases, resulting for rapid treatment and good outcomes for patient. The PCF sensor is unique due to its hollow core decagonal-core structure, which significantly enhances light-matter interaction in the terahertz range and enables accurate cervical cancer cell detection. This innovative method offers a non-invasive, label-free testing procedure with great depth resolution and selectivity, compared to traditional detection approaches.</p>

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High sensitivity cervical cancer detection employing hollow decagonal core photonic crystal fiber in the Terahertz Region

  • Diponkar Kundu,
  • Md Jobaier Hossain,
  • Khalid Sifulla Noor,
  • Md. Safiul Islam,
  • A. H. M. Iftekharul Ferdous,
  • Md. Naimur Rahman Naim,
  • Ramesh Manickam,
  • Mylsamy Karpagam,
  • Ahmed Nabih Zaki Rashed

摘要

A unique hollow core PCF with a decagonal shape, produced by an optical waveform, is created and analytically evaluated. In this paper, on the basis of refractive indices (RI), we detected the most common cancer cells, especially cervical carcinoma, which emerged from HeLa. Additionally, the properties of the guiding of the designed waveguide have been examined. In terms of FEM, a computational tool Comsol Multiphysics 5.6 Software’s are utilized for analyse salient features of the proposed cancer cell sensor. Additionally, to construct the graph of every result, Paint and MATLAB 18a are also used. With regard to cancer cells and normal cells, this detector achieves a relative sensitivity of around 99.845% and 99.50% and CL is 6.24 × 10− 11 dB/m and 2.66 × 10− 12 dB/m at 3.2 THz. This biosensor offers an extremely reliable and precise method for fast detection of Cancer Cell. The innovative method enhances the capability to seance and identify certain diseases, resulting for rapid treatment and good outcomes for patient. The PCF sensor is unique due to its hollow core decagonal-core structure, which significantly enhances light-matter interaction in the terahertz range and enables accurate cervical cancer cell detection. This innovative method offers a non-invasive, label-free testing procedure with great depth resolution and selectivity, compared to traditional detection approaches.