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<p>In 2025, the S2k guideline on early pregnancy loss in the first trimester was published. This guideline covers disrupted early pregnancy and pregnancies of unclear localization resulting in miscarriage, their etiology and risk factors, clinical diagnosis and patient care, as well as pathomorphological diagnostic criteria and recommendations for the macroscopic handling of the abortion tissue and its microscopic processing. In addition to possible causes, the aspects that are important for pathomorphological diagnosis are presented, and the diagnostic criteria mentioned in the guideline are summarized in tables and illustrated with images.</p>

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S2k-Leitlinie Früher Schwangerschaftsverlust im 1. Trimenon

  • 期刊论文

  • 发表日期：

    2026年1月29日

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  • Annette M. Müller,
  • Grit Gesine Ruth Hiller

摘要

In 2025, the S2k guideline on early pregnancy loss in the first trimester was published. This guideline covers disrupted early pregnancy and pregnancies of unclear localization resulting in miscarriage, their etiology and risk factors, clinical diagnosis and patient care, as well as pathomorphological diagnostic criteria and recommendations for the macroscopic handling of the abortion tissue and its microscopic processing. In addition to possible causes, the aspects that are important for pathomorphological diagnosis are presented, and the diagnostic criteria mentioned in the guideline are summarized in tables and illustrated with images.