<p>Hirschsprung disease/aganglionosis of the colon is the most common form of intestinal motility disorder, especially in children. In this review article, which was presented at the specialist meeting of the German Paediatric Pathology Working Group, insight into the histopathological diagnosis of Hirschsprung’s disease, including the technical approach to biopsies, will be provided. In addition, differential diagnoses of chronic intestinal pseudo-obstruction (CIPO), which can be identified with the help of histopathological diagnostics, are presented. These include—among others—hypoganglionosis, intestinal neuronal dysplasia, ganglionitis, and leiomyositis.</p>

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Histopathologische Diagnostik intestinaler Motilitätsstörungen: Morbus Hirschsprung und andere Differentialdiagnosen

  • Thomas Menter

摘要

Hirschsprung disease/aganglionosis of the colon is the most common form of intestinal motility disorder, especially in children. In this review article, which was presented at the specialist meeting of the German Paediatric Pathology Working Group, insight into the histopathological diagnosis of Hirschsprung’s disease, including the technical approach to biopsies, will be provided. In addition, differential diagnoses of chronic intestinal pseudo-obstruction (CIPO), which can be identified with the help of histopathological diagnostics, are presented. These include—among others—hypoganglionosis, intestinal neuronal dysplasia, ganglionitis, and leiomyositis.