<p>The polyvinylidene fluoride (PVDF) composites have emerged as promising materials for Internet of Things (IoT) and electronic skin (E-skin) applications due to their unique piezoelectric properties, stretchability, and biocompatibility. This review is mainly focused on providing an overview of the basic principles, material properties, and cutting-edge applications of PVDF composite materials in IoT and E-Skin. In particular, the properties of PVDF can be increased significantly with the incorporation of suitable fillers and through advanced fabrication techniques such as electrospinning and 3D printing. Notably, the PVDFs discover their applications in IoT devices, including self-powered sensors for environmental monitoring, energy harvesting, and physical activity monitoring. The developed PVDF composites-based flexible and multifunctional E-skin sensors were used for robotics, prosthetics, and biomedical devices, offering capabilities such as tactile sensing, health monitoring, and gesture recognition. Despite the significant progress of these materials, challenges remain in enhancing the piezoelectric coefficients, achieving multi-stimuli sensing, ensuring biocompatibility, and integrating multimodal components. Upcoming research should focus on developing advanced and scalable fabrication techniques, enhancing the energy conversion rate, and creating self-powered systems to integrate PVDF composites into new technologies and contribute to a more intelligent and sustainable future.</p>