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<p>An unexplored fluorescent sheet of Sericin-Chitosan-PVA (SCP) blend was prepared with a combination of Sericin (1%), Chitosan (1%) and PVA (5%) by solvent casting method. The sheet’s analytical characterization was performed by using various techniques, including X-ray diffraction (XRD), thermo-gravimetric analysis (TGA) and Fourier-transform infrared spectroscopy (FTIR) which indicated no polymer-polymer incompatibility. Optical contact angle (OCA) indicated the hydrophobic characteristics of the sheet. Assessing with surface morphology using field emission scanning electron microscopy (FESEM), indicated smooth, flat and porous characteristics of the sheet. The sheets B, C &amp; D showed higher antioxidant potential of more than 10% with DPPH and hydrogen peroxide highlighting that enhanced sericin quantity results in elevated antioxidant properties along with highest mechanical strength in case of sheet C&amp; D of 1.166 MPa &amp; 1.187&#xa0;MPa. Also, sheet B showed very promising results for contact angle of 63.072<sup>0</sup> with surface free energy of 42.88mN/m, indicating its wide acceptability as biomaterial with wound healing potential of all fluorescent sheets tested in mice accelerated healing within a span of 14 days with no visible scars suggesting the application of the sheets as an effective wound dressing material.</p>

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Preparation and assessment of fluorescent sericin-chitosan biomaterial from Antheraea mylitta for wound healing applications

  • 期刊论文

  • 发表日期：

    2025年12月17日

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  • Ananta Sinha,
  • Karmabeer Jena,
  • Trishna Bal,
  • Stuti Ananta,
  • Aditya Dev Rajora,
  • C. Balaji Ayyanar,
  • Puspanjali Parida,
  • N. B. Chowdary

摘要

An unexplored fluorescent sheet of Sericin-Chitosan-PVA (SCP) blend was prepared with a combination of Sericin (1%), Chitosan (1%) and PVA (5%) by solvent casting method. The sheet’s analytical characterization was performed by using various techniques, including X-ray diffraction (XRD), thermo-gravimetric analysis (TGA) and Fourier-transform infrared spectroscopy (FTIR) which indicated no polymer-polymer incompatibility. Optical contact angle (OCA) indicated the hydrophobic characteristics of the sheet. Assessing with surface morphology using field emission scanning electron microscopy (FESEM), indicated smooth, flat and porous characteristics of the sheet. The sheets B, C & D showed higher antioxidant potential of more than 10% with DPPH and hydrogen peroxide highlighting that enhanced sericin quantity results in elevated antioxidant properties along with highest mechanical strength in case of sheet C& D of 1.166 MPa & 1.187 MPa. Also, sheet B showed very promising results for contact angle of 63.0720 with surface free energy of 42.88mN/m, indicating its wide acceptability as biomaterial with wound healing potential of all fluorescent sheets tested in mice accelerated healing within a span of 14 days with no visible scars suggesting the application of the sheets as an effective wound dressing material.