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<p>The challenge of bacterial contamination, which triggers an immune response, remains a significant hurdle in the biomedical field. This study explored the use of exopolymeric substance-capped selenium nanoparticles (EPS-SeNPs) to enhance the antibacterial properties of cotton gauze. The modification of the gauze involved using chitosan as an adhesive agent to improve the deposition of EPS-SeNPs. The resulting functionalized gauze, termed EPS-SeNPs@CH_CG, was further analyzed using physicochemical techniques such as XRD, FTIR, and FE-SEM. This functionalized gauze exhibited both anti-adhesive and bactericidal properties against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i>. A prolonged antibacterial effect was also observed to be facilitated by the sustained release of selenium from the gauze. This study underscores the potential of EPS-SeNPs@CH_CG-functionalized cotton gauze for anti-microbial enhancement which can be an asset for biomedical applications.</p>

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Enhanced antimicrobial properties of cotton gauze functionalized with biosynthesized selenium nanoparticles

  • 期刊论文

  • 发表日期：

    2025年3月4日

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  • Anmol Singh,
  • Priyankar Dey,
  • Hisaaki Mihara,
  • Ranjana Prakash,
  • Nagaraja Tejo Prakash

摘要

The challenge of bacterial contamination, which triggers an immune response, remains a significant hurdle in the biomedical field. This study explored the use of exopolymeric substance-capped selenium nanoparticles (EPS-SeNPs) to enhance the antibacterial properties of cotton gauze. The modification of the gauze involved using chitosan as an adhesive agent to improve the deposition of EPS-SeNPs. The resulting functionalized gauze, termed EPS-SeNPs@CH_CG, was further analyzed using physicochemical techniques such as XRD, FTIR, and FE-SEM. This functionalized gauze exhibited both anti-adhesive and bactericidal properties against Escherichia coli and Staphylococcus aureus. A prolonged antibacterial effect was also observed to be facilitated by the sustained release of selenium from the gauze. This study underscores the potential of EPS-SeNPs@CH_CG-functionalized cotton gauze for anti-microbial enhancement which can be an asset for biomedical applications.