<p>The hydroxyurea is a save, affordable and essential medicine for sickle cell disease (SCD), reducing painful crises and mortality. To foster the prescription of hydroxyurea for patients with SCD in sub-Saharan African countries, the scientific advisory board of Drep.Afrique, a non-governmental organization dedicated to SCD in Africa, has developed a therapeutic guideline well suited to conditions on the ground. These guidelines answer three essential questions: which patients should be prioritized for treatment with hydroxyurea, which dose should be used, and what follow-up should be implemented in those low-resources countries?</p><p> The guidelines are given as in a concise document for easy use by practitioners on the ground, available in English and in French.</p>

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Use of hydroxyurea in French-speaking Sub-Saharan Africa

  • Jean-Benoît Arlet,
  • Françoise Bernaudin,
  • Indou Deme-Ly,
  • Binta Coulibaly,
  • Anne Corbasson,
  • Ibrahima Diagne,
  • Dapa Diallo,
  • Saliou Diop,
  • Charlotte Eposse,
  • Frédéric Galacteros,
  • Olivier Hermine,
  • Eléonore Kafando,
  • Agnès Lainé,
  • Mariane de Montalembert,
  • Constant Vodouhé,
  • Ahoefa Vovor,
  • Brigitte Ranque,
  • Léon Tshilolo

摘要

The hydroxyurea is a save, affordable and essential medicine for sickle cell disease (SCD), reducing painful crises and mortality. To foster the prescription of hydroxyurea for patients with SCD in sub-Saharan African countries, the scientific advisory board of Drep.Afrique, a non-governmental organization dedicated to SCD in Africa, has developed a therapeutic guideline well suited to conditions on the ground. These guidelines answer three essential questions: which patients should be prioritized for treatment with hydroxyurea, which dose should be used, and what follow-up should be implemented in those low-resources countries?

The guidelines are given as in a concise document for easy use by practitioners on the ground, available in English and in French.