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Isolated massive pleural effusion as a manifestation of chronic graft versus host disease successfully treated with corticosteroid

  • Yasutaka Masuda,
  • Sho Yamazaki,
  • Akira Honda,
  • Yosuke Masamoto,
  • Mineo Kurokawa

摘要

Isolated pleural effusion is a rare manifestation of chronic graft versus host disease (cGVHD) after hematopoietic stem cell transplantation (HSCT). We herein report a 58-year-old woman presenting with massive pleural effusion approximately 1 year after allogeneic HSCT, who was successfully treated with corticosteroid. She had discontinued tacrolimus approximately 1 month before she presented with pleural effusion, which was attributed to cGVHD after a thorough exclusion process. This case illustrates a unique manifestation of atypical cGVHD and highlights the need for prompt therapy initiation.