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Purpose <p>This study aims to evaluate the safety and effectiveness of TIPS-PVR in patients with cirrhosis with acute PVT.</p> Materials and Methods <p>A retrospective analysis of cirrhotic patients with acute PVT who underwent TIPS-PVR at a single academic institution. Patients were categorized by PVT etiology and thrombus extent according to AASLD criteria. Outcomes assessed included technical success, one-year patency of the TIPS and porto-mesenteric venous system, need for TIPS reintervention, symptom recurrence, and overall survival. Overall survival was defined as the time from TIPS-PVR to death or last follow-up.</p> Results <p>Fifty cirrhotic patients underwent TIPS-PVR for acute PVT. Technical success was 100%. Superior mesenteric vein (SMV) involvement was seen in 30/50 (60%), and splenic vein in 11/50 (22%). At one year, 32 patients had follow-up. Primary patency was 75% (24/32), primary-assisted patency 94% (30/32) for TIPS and 97% (31/32) for the portal vein. Patency rates improved at one year: Main portal vein from 18 to 97% (<i>p</i> &lt; 0.001), SMV from 50 to 91% (p &lt; 0.001), splenic vein from 78 to 100% (<i>p</i> = 0.0108). 9 patients underwent liver transplantation after TIPS-PVR. There were no grade 4 or grade 5 CIRSE adverse events. There were five Grade 6 events after the procedure. Overall survival was 78% at 12&#xa0;months, with 95% CI 64–87%.</p> Conclusions <p>TIPS-PVR appears to be a safe and effective procedure for cirrhotic patients with acute PVT, offering a viable option for restoring portal venous flow.</p>

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Outcomes of Transjugular Intrahepatic Portosystemic Shunt with Portal Vein Recanalization in Cirrhotic Patients with Acute Portal Vein Thrombosis: A Single-Center Study

  • 期刊论文

  • 发表日期：

    2026年3月14日

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  • Vijay Ramalingam,
  • Zohaa Faiz,
  • Mariam Dogar,
  • Jeffrey Weinstein,
  • Lauren Yang,
  • Jonathan Berry,
  • Michael Curry,
  • Ammar Sarwar,
  • Muneeb Ahmed

摘要

Purpose

This study aims to evaluate the safety and effectiveness of TIPS-PVR in patients with cirrhosis with acute PVT.

Materials and Methods

A retrospective analysis of cirrhotic patients with acute PVT who underwent TIPS-PVR at a single academic institution. Patients were categorized by PVT etiology and thrombus extent according to AASLD criteria. Outcomes assessed included technical success, one-year patency of the TIPS and porto-mesenteric venous system, need for TIPS reintervention, symptom recurrence, and overall survival. Overall survival was defined as the time from TIPS-PVR to death or last follow-up.

Results

Fifty cirrhotic patients underwent TIPS-PVR for acute PVT. Technical success was 100%. Superior mesenteric vein (SMV) involvement was seen in 30/50 (60%), and splenic vein in 11/50 (22%). At one year, 32 patients had follow-up. Primary patency was 75% (24/32), primary-assisted patency 94% (30/32) for TIPS and 97% (31/32) for the portal vein. Patency rates improved at one year: Main portal vein from 18 to 97% (p < 0.001), SMV from 50 to 91% (p < 0.001), splenic vein from 78 to 100% (p = 0.0108). 9 patients underwent liver transplantation after TIPS-PVR. There were no grade 4 or grade 5 CIRSE adverse events. There were five Grade 6 events after the procedure. Overall survival was 78% at 12 months, with 95% CI 64–87%.

Conclusions

TIPS-PVR appears to be a safe and effective procedure for cirrhotic patients with acute PVT, offering a viable option for restoring portal venous flow.