Background <p>This study aimed to evaluate the clinical efficacy and safety of a modified wedge resection technique for composite reduction of labia minora hypertrophy and redundant clitoral hood.</p> Methods <p>A retrospective analysis was conducted on patients who underwent the modified wedge resection procedure for concurrent labia minora and clitoral hood reduction at the Department of Plastic &amp; Cosmetic Surgery, Women’s Hospital of Nanjing Medical University (Nanjing Women and Children’s Healthcare Hospital) between July 2019 and December 2024. Descriptive statistics were used to analyze patient demographics, self-reported symptoms, postoperative complications, symptom improvement, aesthetic satisfaction, and overall satisfaction.</p> Results <p>The study included 738 patients with a mean age of 27.6 ± 6.1 years (range: 18–49). Preoperative motivations and symptoms primarily included vulvar friction discomfort (98.8%), aesthetic concerns (87.1%), dyspareunia (7.9%), and increased residual secretions (7.5%). The mean follow-up duration was 1.9 months (range: 1–6). Postoperative complications consisted of delayed wound healing (24 cases, 3.3%) and perceived asymmetry (10 cases, 1.4%). Preoperative symptoms improved in 99.3% of patients, and 99.2% were satisfied with the aesthetic outcome. Overall, 710 patients (96.2%) reported satisfaction with the surgical results.</p> Conclusion <p>The modified wedge resection technique enables simultaneous correction of labia minora hypertrophy and redundant clitoral hood in a single procedure, yielding consistent and satisfactory aesthetic outcomes. This approach is straightforward, reproducible, and demonstrates favorable clinical safety.</p> Level of Evidence IV <p>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors <a href="http://www.springer.com/00266">www.springer.com/00266</a>.</p>