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<p>The majority of early breast cancer patients undergo breast-conserving surgery and radiotherapy. Radiation therapy can cause complications due to early and late alterations in cellular function leading to fibrosis. Some of them subsequently present for reduction mammoplasty. Reduction mammoplasty is performed both in the irradiated and non-irradiated breasts which could lead to increased complications due to prior radiotherapy.</p><p><i>Level of Evidence III</i>&#xa0;This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors <a href="http://www.springer.com/00266">www.springer.com/00266</a>.</p>

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Letter in Reply to Commentary on “Does Prior Breast Irradiation Increase Complications of Subsequent Reduction Surgery in Breast Cancer Patients? A Systematic Review and Meta-analysis”

  • 期刊论文

  • 发表日期：

    2025年5月8日

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  • George Pappas,
  • Femi E. Ayeni,
  • Senarath Edirimanne

摘要

The majority of early breast cancer patients undergo breast-conserving surgery and radiotherapy. Radiation therapy can cause complications due to early and late alterations in cellular function leading to fibrosis. Some of them subsequently present for reduction mammoplasty. Reduction mammoplasty is performed both in the irradiated and non-irradiated breasts which could lead to increased complications due to prior radiotherapy.

Level of Evidence III This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.