Background <p>The celiac trunk is the first anterior branch of abdominal aorta. Celiac trunk and hepatic arteries show several variations in origin and course, knowledge of which is important during open and laparoscopic surgeries. Preoperative assessment of variants helps to reduce complications like vascular bleeding. The celiac trunk and hepatic artery branching patterns can be assessed with contrast-enhanced abdominal CT. This study will offer the types of variants observed in the Ethiopian population, helping to mitigate the morbidity and mortality associated with variant anatomies.</p> Methods <p>A hospital-based retrospective chart review study was conducted from June –August 2024, among patients who underwent abdominal MDCT from June 2023 to May 2024. A total of 290 triphasic abdominal MDCTs were included in the study using a single-proportion population formula. The data was collected from abdominal CT images by radiologists. The data was managed with epi-info, and descriptive and comparative inferential statistics were done by SPSS version 27.</p> Results <p>About 84.83% of the cases showed a normal trifurcation pattern of the celiac trunk (Uflacker type I), with the commonest variant being the gastro-splenic trunk (Uflacker type V), with a 7.24% incidence. Regarding the hepatic artery, 69.7% of the cases showed the normal origin of the hepatic arteries (Michel type I), with the commonest variant being Michel type V with a 9.31% incidence. Some cases are discovered that were not previously described by Michel’s classifications.</p> Conclusion <p>Our study revealed that variations in the celiac trunk and hepatic arteries are common. Significant correlations between variant right and left hepatic arteries were noted. We recommend that interventional and body imaging radiologists, as well as hepatobiliary and liver transplant surgeons, be aware of the specific variations in the celiac trunk and hepatic arteries to mitigate associated complications.</p>