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<p>Advances in imaging techniques have evolved, allowing for early noninvasive diagnosis and improved management of high-risk patients with hepatocellular carcinoma (HCC). The hallmark imaging features of HCC on multiphasic cross-sectional imaging can be explained by the multistep process of hepatocarcinogenesis and is seen in 60% of cases. However, approximately 40% of cases do not abide by the classic imaging appearance and may pose a diagnostic challenge for radiologists. These may be accounted by their morphologic subtypes with differing molecular and/or genetic features. Additionally, various malignant and benign lesions and pseudolesions may mimic HCC. This article aims to highlight the unusual cross-sectional imaging manifestations of HCC and describe its pitfalls and mimics.</p>

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Magnetic resonance imaging of hepatocellular carcinoma: a spectrum of uncommon morphologic subtypes, unusual imaging patterns and mimics

  • 期刊论文

  • 发表日期：

    2025年1月4日

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  • Mindy X. Wang,
  • M. Azfar Siddiqui,
  • Alexandra Roudenko,
  • Amita Kamath,
  • Humaira Chaudhry,
  • Roopa Ram,
  • Amir A. Borhani,
  • Venkateswar Surabhi,
  • Khaled M. Elsayes,
  • Robert M. Marks,
  • Maxime Ronot

摘要

Advances in imaging techniques have evolved, allowing for early noninvasive diagnosis and improved management of high-risk patients with hepatocellular carcinoma (HCC). The hallmark imaging features of HCC on multiphasic cross-sectional imaging can be explained by the multistep process of hepatocarcinogenesis and is seen in 60% of cases. However, approximately 40% of cases do not abide by the classic imaging appearance and may pose a diagnostic challenge for radiologists. These may be accounted by their morphologic subtypes with differing molecular and/or genetic features. Additionally, various malignant and benign lesions and pseudolesions may mimic HCC. This article aims to highlight the unusual cross-sectional imaging manifestations of HCC and describe its pitfalls and mimics.