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The snowflake sign

  • Davide Castiglione,
  • Francesco Tiralongo,
  • Renato Farina,
  • Emanuele David,
  • Antonio Basile

摘要

The “snowflake sign” in liver brucellosis refers to a characteristic appearance on radiological imaging. It is caused by a calcified granuloma within the liver, resulting from a chronic Brucella infection. This calcification often has a distinctive “snowflake” pattern due to its radiating, irregular shape. This sign can be a valuable clue in diagnosing hepatic brucellosis, especially in regions where the disease is endemic.