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<p>Olfactory schwannoma is a very rare tumor, whose origin is still under investigation. We report the case of a 16-year-old adolescent who presented with worsening headaches, hyposmia, and a convulsive crisis. Brain imaging showed a frontobasal lesion, attached to the cribriform plate, with solid and multiseptated cystic components. The patient underwent complete resection of the lesion. A comprehensive molecular study confirmed a methylation pattern consistent with schwannoma. Although rare, olfactory schwannomas should be considered in the differential diagnosis of anterior cranial fossa tumors. Given its benign nature, a complete resection leads to favorable long-term outcomes.</p> Graphical Abstract <p></p>

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Olfactory schwannoma in an adolescent: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月5日

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  • Rita de Sousa,
  • Francisco Miguel Rodrigues,
  • Carolina Maia,
  • Alice Carvalho,
  • Inês Luz,
  • Gustavo Soares,
  • Ana Margarida Novo,
  • Olinda Rebelo,
  • Stephan Frank,
  • Jürgen Hench,
  • Sílvia Carvalho

摘要

Olfactory schwannoma is a very rare tumor, whose origin is still under investigation. We report the case of a 16-year-old adolescent who presented with worsening headaches, hyposmia, and a convulsive crisis. Brain imaging showed a frontobasal lesion, attached to the cribriform plate, with solid and multiseptated cystic components. The patient underwent complete resection of the lesion. A comprehensive molecular study confirmed a methylation pattern consistent with schwannoma. Although rare, olfactory schwannomas should be considered in the differential diagnosis of anterior cranial fossa tumors. Given its benign nature, a complete resection leads to favorable long-term outcomes.

Graphical Abstract