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<p>Non-immune hydrops fetalis (NIHF) is a complex perinatal diagnosis with diverse and often idiopathic causes, including impaired lymphatic drainage and compromised venous return. We present the case of a newborn with large bilateral pleural effusions who was subsequently found to have a hypoplastic superior vena cava (SVC). Initially treated with thoracentesis and dietary changes, the infant's symptoms persisted. Follow-up imaging confirmed ongoing SVC narrowing, which was successfully treated with a stent. This case underscores the importance of identifying non-traditional causes of NIHF.</p>

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Long-Segment Superior Vena Cava Hypoplasia as an Uncommon Cause of Non-immune Hydrops Fetalis

  • 期刊论文

  • 发表日期：

    2025年9月23日

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  • Alexandra N. Vega,
  • Zeromeh Gerber,
  • Christopher Herron

摘要

Non-immune hydrops fetalis (NIHF) is a complex perinatal diagnosis with diverse and often idiopathic causes, including impaired lymphatic drainage and compromised venous return. We present the case of a newborn with large bilateral pleural effusions who was subsequently found to have a hypoplastic superior vena cava (SVC). Initially treated with thoracentesis and dietary changes, the infant's symptoms persisted. Follow-up imaging confirmed ongoing SVC narrowing, which was successfully treated with a stent. This case underscores the importance of identifying non-traditional causes of NIHF.