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Background <p>Necrotizing fasciitis (NF) is a rapidly progressive and life-threatening soft tissue infection associated with significant morbidity and mortality. Diagnosing early and prompt surgical management are crucial, to improve patient outcomes.</p> <p>We aimed to evaluate the demographic characteristics, clinical presentation, comorbidities, treatment modalities, and outcomes of patients with necrotizing fasciitis treated at the University Clinical Center of Kosovo between 2011 and 2020, and to compare findings with previously reported data from the same institution.</p> Methods <p>An observational retrospective study was conducted in patients diagnosed with necrotizing fasciitis. Data were collected from medical records and included demographic characteristics, comorbidities, anatomical localization, microbiological findings, number of surgical interventions, and length of hospital stay. Descriptive statistical analysis was performed.</p> Results <p>A total of 94 patients were included, with a slight female predominance (53.2%). The mean age was 55.5 ± 12.6 years (median 58, range 24–87). The femoral region was the most commonly affected site (39.4%). Diabetes mellitus was the most frequent accompanying disease (40.4%), while 22.3% of patients had no prior diseases. The mean length of hospital stay was 31 days. Most patients (45.7%) required 2–3 surgical procedures. Polymicrobial infections were identified in 52.4% of cases. Compared to earlier data from the same center, a more balanced sex distribution and shorter hospitalization duration were observed.</p> Conclusions <p>Necrotizing fasciitis remains a severe condition requiring early recognition and aggressive multidisciplinary management. Diabetes mellitus continues to be the most significant risk factor, and repeated surgical debridement is often necessary. Improvements in clinical management may have contributed to reduced hospital stay and changing epidemiological patterns over time. Level of Evidence: Level IV, risk / prognostic study.</p>

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A decade of our experience with necrotizing fasciitis at the university clinical center of Kosovo: a retrospective study of 94 patients (2011–2020)

  • 期刊论文

  • 发表日期：

    2026年6月30日

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  • Edrina M Bektashi,
  • Shkelzen B Duci,
  • Violeta K Zatriqi,
  • Dile A Rusta,
  • Nora K Markaj,
  • Mimoza E Selmani

摘要

Background

Necrotizing fasciitis (NF) is a rapidly progressive and life-threatening soft tissue infection associated with significant morbidity and mortality. Diagnosing early and prompt surgical management are crucial, to improve patient outcomes.

We aimed to evaluate the demographic characteristics, clinical presentation, comorbidities, treatment modalities, and outcomes of patients with necrotizing fasciitis treated at the University Clinical Center of Kosovo between 2011 and 2020, and to compare findings with previously reported data from the same institution.

Methods

An observational retrospective study was conducted in patients diagnosed with necrotizing fasciitis. Data were collected from medical records and included demographic characteristics, comorbidities, anatomical localization, microbiological findings, number of surgical interventions, and length of hospital stay. Descriptive statistical analysis was performed.

Results

A total of 94 patients were included, with a slight female predominance (53.2%). The mean age was 55.5 ± 12.6 years (median 58, range 24–87). The femoral region was the most commonly affected site (39.4%). Diabetes mellitus was the most frequent accompanying disease (40.4%), while 22.3% of patients had no prior diseases. The mean length of hospital stay was 31 days. Most patients (45.7%) required 2–3 surgical procedures. Polymicrobial infections were identified in 52.4% of cases. Compared to earlier data from the same center, a more balanced sex distribution and shorter hospitalization duration were observed.

Conclusions

Necrotizing fasciitis remains a severe condition requiring early recognition and aggressive multidisciplinary management. Diabetes mellitus continues to be the most significant risk factor, and repeated surgical debridement is often necessary. Improvements in clinical management may have contributed to reduced hospital stay and changing epidemiological patterns over time. Level of Evidence: Level IV, risk / prognostic study.