Scholarlink

<p>A rare extra- and intracranial mixed vascular malformation involving the scalp soft tissues and the dura mater, associated with skull erosion, and characterized by both a low-flow capillary–venous component and a high-flow component consistent with a dural arteriovenous fistula involving a diploic vein, represents a complex therapeutic challenge. An 18-year-old man underwent multimodal imaging for evaluation of non-disabling headaches and intermittent pulsatile sensation. MRI and CT demonstrated focal calvarial erosion, while MRA and digital subtraction angiography revealed a direct shunt between the middle meningeal artery and a diploic vein, in addition to a diffuse low-flow capillary–venous network supplied by branches of the external carotid artery and the middle meningeal artery. Treatment consisted of selective embolization of the shunt using n-butyl cyanoacrylate, followed by intra-arterial bleomycin administration combined with reversible electroporation targeting the slow-flow component. At 6-month follow-up, the patient was asymptomatic, with only localized alopecia at electrode application sites. Follow-up MRI demonstrated near-complete resolution of the dural component and marked reduction of the extracranial lesion, indicating a favorable clinical and radiological outcome.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Bleomycin electroembolotherapy in a rare mixed extra- and intracranial scalp–dural vascular malformation with high- and low-flow components

  • 期刊论文

  • 发表日期：

    2026年5月7日

查看全文
  • Francesco Mistretta,
  • Riccardo Russo,
  • Stefano Molinaro,
  • Umberto Amedeo Gava,
  • Mattia Mastrangelo,
  • Jacopo Brino,
  • Andrea Discalzi,
  • Floriana Nardelli,
  • Margherita Viglione,
  • Francesco Praticò,
  • Mauro Bergui

摘要

A rare extra- and intracranial mixed vascular malformation involving the scalp soft tissues and the dura mater, associated with skull erosion, and characterized by both a low-flow capillary–venous component and a high-flow component consistent with a dural arteriovenous fistula involving a diploic vein, represents a complex therapeutic challenge. An 18-year-old man underwent multimodal imaging for evaluation of non-disabling headaches and intermittent pulsatile sensation. MRI and CT demonstrated focal calvarial erosion, while MRA and digital subtraction angiography revealed a direct shunt between the middle meningeal artery and a diploic vein, in addition to a diffuse low-flow capillary–venous network supplied by branches of the external carotid artery and the middle meningeal artery. Treatment consisted of selective embolization of the shunt using n-butyl cyanoacrylate, followed by intra-arterial bleomycin administration combined with reversible electroporation targeting the slow-flow component. At 6-month follow-up, the patient was asymptomatic, with only localized alopecia at electrode application sites. Follow-up MRI demonstrated near-complete resolution of the dural component and marked reduction of the extracranial lesion, indicating a favorable clinical and radiological outcome.