<p>The employment of amino acids as green fast-reacting biodegradable solvents for CO₂ capture has been recently considered a viable option owing to their elevated solubility for CO₂. However, in the application of L-lysine as an absorbent for CO₂ capture, there is no comprehensive understanding of the continuous mass transfer process in gas-liquid contactors, which leads to the lack of guidance for the industrial flue gas decarbonization processes. To enhance the mass transfer of CO₂ capture utilizing incorporated alkanolamine solutions along with elucidate the impact of amino-acid incorporation, the capability of a novel multi-component absorbent, including methyldiethanolamine (MDEA), diisopropanolamine (DIPA), and L-lysine (Lys) was assessed for the first time in a tree-shaped parallel micro-contactor. The CO₂ capture percent, total volumetric gas-phase mass transfer coefficient (TGMTC), and CO₂ molar flux (<i>N</i>_<i>A</i><i>a</i>_<i>V</i>) were explored over an entire range of feed gas flow rate (60–240 mL/min), mixed absorbent flow rate (3–9 mL/min), CO₂ concentration in the feed (5–15 vol%), and absorption temperature (25–45 ˚C). Under a given temperature of 40˚C, the TGMTC value attained its peak at 47.52 kmol/m³.h.kPa with a concentration of MDEA-DIPA-Lys (30-3-7) wt% under a Q_g= 240 mL/min, and Q_l=9 mL/min. Besides, in comparison to the aqueous pure solution of MDEA, the values of the <i>N</i>_<i>A</i><i>a</i>_<i>V</i> and TGMTC for the ternary MDEA-DIPA-Lys solution has been enhanced by 3.21 and 3.34 times, respectively. This illustrates the possible benefit of green L-lysine amino acid within the MDEA-DIPA mixture concerning the CO₂ absorption process.</p>