Scholarlink

<p>Schizophrenia (SCZ) is a complex, comprehensible mental condition that creates alienation from reality. SCZ is a mental disease, which is marked by progressive deficits in working memory, attention, and executive functioning. Because the disease’s etiology is unknown, current psychotherapy and pharmacological treatments merely treat symptoms and do not provide a cure. SCZ symptoms include hallucinations, delusions, disorganized behavior, and lack of desire. Long-term use of antipsychotic (antagonists at multiple G-protein-coupled receptors) (mGPCR antagonists) medicines for therapy has negative health consequences and discourages patients from taking regular medication. Ancient herbal therapies are regaining popularity in disease management due to their natural origins, less side effects, and cost-effectiveness. The various types of phytochemicals include alkaloids, glycosides, polyphenols, terpenes and terpenoids, phytosterols, cannabinoids, and carotenoids could be used as mGPCR antagonists. In this review, we documented the possibility of employing natural compounds as an alternative therapy to treat schizophrenia-related symptoms and cognitive impairments.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A comprehensive review on schizophrenia: epidemiology, pathogenesis, diagnosis, conventional treatments, and proposed natural compounds used for management

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年6月13日

查看全文
  • Alaa Anwar,
  • Aya M. Mustafa,
  • Kareem Abdou,
  • Mostafa A. Rabie,
  • Riham A. El-Shiekh,
  • Ahmed M. El-Dessouki

摘要

Schizophrenia (SCZ) is a complex, comprehensible mental condition that creates alienation from reality. SCZ is a mental disease, which is marked by progressive deficits in working memory, attention, and executive functioning. Because the disease’s etiology is unknown, current psychotherapy and pharmacological treatments merely treat symptoms and do not provide a cure. SCZ symptoms include hallucinations, delusions, disorganized behavior, and lack of desire. Long-term use of antipsychotic (antagonists at multiple G-protein-coupled receptors) (mGPCR antagonists) medicines for therapy has negative health consequences and discourages patients from taking regular medication. Ancient herbal therapies are regaining popularity in disease management due to their natural origins, less side effects, and cost-effectiveness. The various types of phytochemicals include alkaloids, glycosides, polyphenols, terpenes and terpenoids, phytosterols, cannabinoids, and carotenoids could be used as mGPCR antagonists. In this review, we documented the possibility of employing natural compounds as an alternative therapy to treat schizophrenia-related symptoms and cognitive impairments.