Let \(\Gamma \) be the hyperbola \(\{(x,y)\in \mathbb {R}^2:xy=1\}\) and \(\Lambda _{\alpha , \beta ,\theta _1, \theta _2}\) be the perturbed lattice-cross defined by \(\Lambda _{\alpha , \beta , \theta _1, \theta _2}=\left( (\alpha \mathbb Z+\{\theta _1\})\times \{0\}\right) \cup \left( \{0\}\times (\beta \mathbb Z+\{\theta _2\})\right) \) in \(\mathbb {R}^2\) , where \(\theta _1, \theta _2\in \mathbb R,\) and \(\alpha , \beta \) are positive reals. Under certain conditions on the parameters \(\alpha , \beta ,\theta _1\) and \(\theta _2\) , we study necessary and sufficient conditions for Heisenberg uniqueness pairs corresponding to the hyperbola. Our method of proof is inspired by the work of Hedenmalm and Montes-Rodríguez where they considered the classical case, that is, \(\theta _1=\theta _2=0\) . Moreover, we answer an interesting question raised by Canto-Martín, Hedenmalm, and Montes-Rodríguez, related to an explicit formulation of the certain pre-annihilator space.