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<p>The growing demand for innovative and pesticide-free pest management in global food production has accelerated the development of environmentally friendly alternatives. Among these, biopesticides based on <i>Bacillus thuringiensis</i> (Bt) have emerged as a leading substitute. Renowned for their specificity and effectiveness in controlling agricultural pests, Bt biopesticides face limitations in field applications, primarily due to formulation instability and degradation of insecticidal proteins under ultraviolet (UV) exposure. Recent advancements in formulation have provided new opportunities for creating more efficient formulations of Bt that can address these challenges, enabling the development of more stable, efficient, and targeted Bt formulations. This review highlights recent advancements in formulation, including nanotechnological approaches for improving Bt-based biopesticides. Nanotechnological approaches include encapsulation techniques, coating, nanopesticides, nanoemulsions, nanosuspensions, nano-carriers for targeted delivery, and nano-formulations for controlled release and pest specificity. These interventions to enhance the efficiency and sustainability of Bt-based biopesticides can increase their adoption in agricultural pest management around the globe.</p>

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Nanotechnological approaches for the improvement of field efficacy of Bacillus thuringiensis-based biopesticides

  • 期刊论文

  • 发表日期：

    2026年3月14日

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  • B. D. Ghodake,
  • M. P. Moharil,
  • Shreshtha Saxena,
  • Ankita V. Chinche,
  • Avinash P. Ingle,
  • Aniket K. Gade

摘要

The growing demand for innovative and pesticide-free pest management in global food production has accelerated the development of environmentally friendly alternatives. Among these, biopesticides based on Bacillus thuringiensis (Bt) have emerged as a leading substitute. Renowned for their specificity and effectiveness in controlling agricultural pests, Bt biopesticides face limitations in field applications, primarily due to formulation instability and degradation of insecticidal proteins under ultraviolet (UV) exposure. Recent advancements in formulation have provided new opportunities for creating more efficient formulations of Bt that can address these challenges, enabling the development of more stable, efficient, and targeted Bt formulations. This review highlights recent advancements in formulation, including nanotechnological approaches for improving Bt-based biopesticides. Nanotechnological approaches include encapsulation techniques, coating, nanopesticides, nanoemulsions, nanosuspensions, nano-carriers for targeted delivery, and nano-formulations for controlled release and pest specificity. These interventions to enhance the efficiency and sustainability of Bt-based biopesticides can increase their adoption in agricultural pest management around the globe.