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Background <p>In 2024 cannabis consumption was partially legalized in Germany, a&#xa0;tetrahydrocannabinol (THC) limit of 3.5 ng/ml blood serum was established in the German Road Traffic Act (StVG) and the semisynthetic cannabinoid hexahydrocannabinol (HHC) was added to the German New Psychoactive Substances Act (NpSG). The aim of this study was to provide initial insights into the impact of these legislative changes from a&#xa0;forensic toxicological perspective.</p> Methods <p>A&#xa0;retrospective data analysis was conducted evaluating available data from the region of Southwest Saxony during the relevant time periods. The focus was laid on the blood concentrations of THC, 11-hydroxy-THC (11-OH-THC), THC carboxylic acid (THC-COOH), (9<i>R</i>)-HHC and (9<i>S</i>)-HHC.</p> Results <p>Since the partial legalization, the detected concentrations of THC, 11-OH-THC and THC-COOH have been significantly higher compared to the same period in 2023. This appears to be primarily due to a&#xa0;higher proportion of regular cannabis users. The increase of the THC limit to 3.5 ng/ml resulted in the nonprosecution of administrative offenses in 27.2% of cases compared to the previous threshold of 1.0 ng/ml. Since HHC was classified under the NpSG and in connection with the partial legalization of cannabis, its consumption has significantly declined.</p> Discussion <p>These initial findings clearly demonstrate that the legislative changes implemented last year have led to shifts in both cannabis consumption patterns and the prosecution of administrative offenses. Further analyses from other regions in Germany are necessary to potentially provide recommendations for corrective measures.</p>

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Cannabinoide im Wandel des Rechts

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年6月5日

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  • Lisa Höfert,
  • Sven Baumann,
  • Jan Dreßler,
  • Susen Becker

摘要

Background

In 2024 cannabis consumption was partially legalized in Germany, a tetrahydrocannabinol (THC) limit of 3.5 ng/ml blood serum was established in the German Road Traffic Act (StVG) and the semisynthetic cannabinoid hexahydrocannabinol (HHC) was added to the German New Psychoactive Substances Act (NpSG). The aim of this study was to provide initial insights into the impact of these legislative changes from a forensic toxicological perspective.

Methods

A retrospective data analysis was conducted evaluating available data from the region of Southwest Saxony during the relevant time periods. The focus was laid on the blood concentrations of THC, 11-hydroxy-THC (11-OH-THC), THC carboxylic acid (THC-COOH), (9R)-HHC and (9S)-HHC.

Results

Since the partial legalization, the detected concentrations of THC, 11-OH-THC and THC-COOH have been significantly higher compared to the same period in 2023. This appears to be primarily due to a higher proportion of regular cannabis users. The increase of the THC limit to 3.5 ng/ml resulted in the nonprosecution of administrative offenses in 27.2% of cases compared to the previous threshold of 1.0 ng/ml. Since HHC was classified under the NpSG and in connection with the partial legalization of cannabis, its consumption has significantly declined.

Discussion

These initial findings clearly demonstrate that the legislative changes implemented last year have led to shifts in both cannabis consumption patterns and the prosecution of administrative offenses. Further analyses from other regions in Germany are necessary to potentially provide recommendations for corrective measures.