<p>The high-pressure CO₂ cryogenic cooling technology has outstanding performance in improving the cutting zone temperature and cutting force of the aerospace alloy Ti-6Al-4&#xa0;V, and it is of great practical significance to study the improvement ability of this technology and provide a prediction model. The research employs a hybrid modeling method combining computational fluid dynamics (CFD) and finite element method (FEM). In the CFD numerical simulation model, the condensed phase transition of high-pressure CO₂ is considered with an Eulerian two-phase flow method, which is embedded into this CFD model through a User-Defined Function (UDF). The axial temperature and minimum temperature of jet field are verified experimentally by thermocouple temperature measurement. A coupled heat-fluid–solid model is developed by adding a tool heat source at the lowest point of the temperature to obtain the convective heat transfer coefficient between the high-pressure CO₂ cryogenic cooling jet and the cutting zone. The coefficient is imported into the developed FE model to obtain the temperature and cutting forces. The simulation and experimental results show that the high-pressure CO₂ jet of 5&#xa0;MPa has the best cooling effect when it is about 1.5&#xa0;mm away from the nozzle outlet. The hybrid model and cutting experiment results show that the model has a good prediction effect in the range of 40–130&#xa0;m/min cutting speed. The prediction error in cutting zone temperature using high-pressure CO₂-assisted cutting compared to dry cutting ranges from 2.62 to 12.22%, demonstrating the accuracy of the flow field simulation. Besides, the minimum and maximum prediction errors are 5.74% and 14.7 for the main cutting force and 0.54% and 14.2% for the thrust force, respectively. The hybrid modeling method proposed in this study has excellent prediction effect and can be used to guide the machining field.</p>