<p>The problem of interaction of multiple (three) edge cracks in an anisotropic half-infinite plane under tension loading is considered. In particular, we focus on the effect of anisotropy axes orientation on the mechanics of edge crack interactions, such as stress shielding. These factors are of the key importance for processes of crack nucleation and growth under various loading conditions, as well as crack kinking. We analyze these effects by stress intensity factors calculations. Calculations were performed for the orthotropic materials and materials with cubic symmetry. The effect of anisotropy was examined by comparison of the results with the ones for the isotropic material. It is demonstrated, that rotation of material anisotropy axes leads to asymmetry of normal stress distribution and controls mixed mode loading on cracks that deflects cracks from straight-line direction. The results indicated that rotation of anisotropy axes can decrease or increase shielding effect by several times comparing to isotropic material and this effect depends on material anisotropy. Decreasing crack length increase shielding effect by several times.</p>