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<p>Drug therapy is a central component of endometriosis treatment and is primarily aimed at controlling pain-related symptoms and suppressing disease activity. The current S2k guideline recommends individualized, symptom-oriented therapy that takes into account the patient’s specific situation, any desire to have children, and the side effect profile. Progestins and oral gonadotropin-releasing hormone (GnRH) antagonists (these after previous surgery) constitute first-line therapy. Although GnRH agonists are effective options for treatment-refractory cases or specific situations, they require careful management of side effects. The choice of therapy should always be made within the context of long-term disease management.</p>

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Medikamentöse Therapie der Endometriose

  • 期刊论文

  • 发表日期：

    2026年7月6日

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  • Stefanie Burghaus

摘要

Drug therapy is a central component of endometriosis treatment and is primarily aimed at controlling pain-related symptoms and suppressing disease activity. The current S2k guideline recommends individualized, symptom-oriented therapy that takes into account the patient’s specific situation, any desire to have children, and the side effect profile. Progestins and oral gonadotropin-releasing hormone (GnRH) antagonists (these after previous surgery) constitute first-line therapy. Although GnRH agonists are effective options for treatment-refractory cases or specific situations, they require careful management of side effects. The choice of therapy should always be made within the context of long-term disease management.