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<p>Endometrial cancer increasingly affects premenopausal women and presents a&#xa0;particular challenge in the implementation of guideline-based standard therapy, especially in patients wishing to preserve fertility. Fertility-sparing treatments therefore require clearly defined inclusion criteria and close oncological monitoring. Based on current European and German guidelines and taking into consideration endocrine treatment strategies, a&#xa0;conservative approach is acceptable in low-risk neoplasms with favorable histological, molecular genetics, and clinical profiles. However, interdisciplinary care and a&#xa0;strong commitment to patient compliance are essential.</p>

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Fertilitätserhalt beim Endometriumkarzinom – Möglichkeiten und Grenzen

  • 期刊论文

  • 发表日期：

    2025年12月22日

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  • Tanja N. Fehm,
  • Emely C. Dreher,
  • Camila Hoyos Banchon,
  • Jan-Steffen Krüssel

摘要

Endometrial cancer increasingly affects premenopausal women and presents a particular challenge in the implementation of guideline-based standard therapy, especially in patients wishing to preserve fertility. Fertility-sparing treatments therefore require clearly defined inclusion criteria and close oncological monitoring. Based on current European and German guidelines and taking into consideration endocrine treatment strategies, a conservative approach is acceptable in low-risk neoplasms with favorable histological, molecular genetics, and clinical profiles. However, interdisciplinary care and a strong commitment to patient compliance are essential.