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<p>Preterm birth is the leading cause of increased morbidity and mortality in childhood, making its prevention a central focus in obstetrics. In addition to behavioral interventions, surgical and pharmacological measures, adequate nutrition forms the foundation of prevention. Supplementation should be tailored individually based on the women’s circumstances or laboratory findings. Progesterone can be considered for patients with a history of spontaneous preterm birth or for women with a short cervix before 24 weeks of gestation. Studies showed that L‑arginine can reduce the risk of pre-eclampsia-related preterm births. In contrast, oral magnesium has not demonstrated a significant effect. Iron deficiency should be identified and treated early. Furthermore, adequate calcium intake is associated with a modest reduction in preterm birth rates. Numerous studies suggest that high-dose ω‑3 fatty acids have a positive effect on reducing the risk of preterm birth.</p>

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Von Progesteron bis zu Supplementen – was kann Frühgeburten verhindern?

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月11日

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  • Christina Louisa Coelius,
  • Verena Boßung

摘要

Preterm birth is the leading cause of increased morbidity and mortality in childhood, making its prevention a central focus in obstetrics. In addition to behavioral interventions, surgical and pharmacological measures, adequate nutrition forms the foundation of prevention. Supplementation should be tailored individually based on the women’s circumstances or laboratory findings. Progesterone can be considered for patients with a history of spontaneous preterm birth or for women with a short cervix before 24 weeks of gestation. Studies showed that L‑arginine can reduce the risk of pre-eclampsia-related preterm births. In contrast, oral magnesium has not demonstrated a significant effect. Iron deficiency should be identified and treated early. Furthermore, adequate calcium intake is associated with a modest reduction in preterm birth rates. Numerous studies suggest that high-dose ω‑3 fatty acids have a positive effect on reducing the risk of preterm birth.