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<p>Pre-eclampsia (PE) affects 2–4% of all pregnancies and is associated with significant morbidity and mortality for mother and child [<CitationRef CitationID="CR1">1</CitationRef>]. Pre-eclampsia screening in the first trimester should be offered to all pregnant women in Germany according to the current AWMF (<i>Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften</i>) guideline. While low-dose aspirin (LDA) reduces the risk of preterm pre-eclampsia (pPE) by 62–75%, LDA has shown only minimal to no effect on the occurrence of term pre-eclampsia (tPE; [<CitationRef CitationID="CR2">2</CitationRef>]). In fact, 75% of all pre-eclampsia is tPE, for which there is no established screening and the only treatment is induction of labour. New studies show that screening at 35–36&#xa0;weeks of pregnancy with targeted induction of labor from 37&#xa0;weeks of pregnancy could significantly reduce the risk of tPE.</p>

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Präeklampsie-Screening im dritten Trimenon

  • 期刊论文

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  • 发表日期：

    2025年6月26日

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  • Thabea Musik,
  • Beatrice Mosimann

摘要

Pre-eclampsia (PE) affects 2–4% of all pregnancies and is associated with significant morbidity and mortality for mother and child [1]. Pre-eclampsia screening in the first trimester should be offered to all pregnant women in Germany according to the current AWMF (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften) guideline. While low-dose aspirin (LDA) reduces the risk of preterm pre-eclampsia (pPE) by 62–75%, LDA has shown only minimal to no effect on the occurrence of term pre-eclampsia (tPE; [2]). In fact, 75% of all pre-eclampsia is tPE, for which there is no established screening and the only treatment is induction of labour. New studies show that screening at 35–36 weeks of pregnancy with targeted induction of labor from 37 weeks of pregnancy could significantly reduce the risk of tPE.